Transconjunctival sinusotomy using the 193‐nm excimer laser

Mauro Campos; Paul P. Lee; Stephen L. Trokel; Hugh R. Taylor; Peter J. McDonnell

doi:10.1111/j.1755-3768.1994.tb04685.x

Transconjunctival sinusotomy using the 193‐nm excimer laser

Mauro Campos, Paul P. Lee, Stephen L. Trokel, Hugh R. Taylor, Peter J. McDonnell

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Abstract. Successful surgical management of glaucoma is limited as a consequence of undesired fibroblastic response of episcleral tissues. In 10 rabbit and three human eye bank eyes, we have performed a modified sinusotomy procedure using the 193‐nm excimer laser. The technique is minimally invasive. Conjunctiva is pulled over the corneoscleral limbus, and a slit‐shaped (1times2 mm) excimer beam ablates through conjunctiva and external sclera until penetrating the outer wall of Schlemm's canal, at which time brisk egress of fluid is noted. The conjunctiva is allowed to retract, and a conjunctival bleb is formed. A single suture is used to close the conjunctival defect. Intraocular pressure in the rabbit eye was decreased from 10.0 ± 1.8 to 4.9 ± 1.8 mmHg immediately after surgery (p < 0.0001). Histology revealed a partial thickness, smooth‐walled ablation consistent with a sinusotomy. This procedure is minimally invasive and may be useful for management of glaucoma, particularly when a substantial component of the impediment to aqueous outflow is external to the trabecular meshwork. 1994 Institution Acta Ophthalmologica Scandinavica

Original language	English (US)
Pages (from-to)	707-711
Number of pages	5
Journal	Acta Ophthalmologica
Volume	72
Issue number	6
DOIs	https://doi.org/10.1111/j.1755-3768.1994.tb04685.x
State	Published - Dec 1994
Externally published	Yes

Keywords

animal model
excimer laser
glaucoma
sinusotomy
transconjunctival filtration surgery

ASJC Scopus subject areas

Ophthalmology

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10.1111/j.1755-3768.1994.tb04685.x

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title = "Transconjunctival sinusotomy using the 193‐nm excimer laser",

abstract = "Abstract. Successful surgical management of glaucoma is limited as a consequence of undesired fibroblastic response of episcleral tissues. In 10 rabbit and three human eye bank eyes, we have performed a modified sinusotomy procedure using the 193‐nm excimer laser. The technique is minimally invasive. Conjunctiva is pulled over the corneoscleral limbus, and a slit‐shaped (1times2 mm) excimer beam ablates through conjunctiva and external sclera until penetrating the outer wall of Schlemm's canal, at which time brisk egress of fluid is noted. The conjunctiva is allowed to retract, and a conjunctival bleb is formed. A single suture is used to close the conjunctival defect. Intraocular pressure in the rabbit eye was decreased from 10.0 ± 1.8 to 4.9 ± 1.8 mmHg immediately after surgery (p < 0.0001). Histology revealed a partial thickness, smooth‐walled ablation consistent with a sinusotomy. This procedure is minimally invasive and may be useful for management of glaucoma, particularly when a substantial component of the impediment to aqueous outflow is external to the trabecular meshwork. 1994 Institution Acta Ophthalmologica Scandinavica",

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AU - Lee, Paul P.

AU - Trokel, Stephen L.

AU - Taylor, Hugh R.

AU - McDonnell, Peter J.

PY - 1994/12

Y1 - 1994/12

N2 - Abstract. Successful surgical management of glaucoma is limited as a consequence of undesired fibroblastic response of episcleral tissues. In 10 rabbit and three human eye bank eyes, we have performed a modified sinusotomy procedure using the 193‐nm excimer laser. The technique is minimally invasive. Conjunctiva is pulled over the corneoscleral limbus, and a slit‐shaped (1times2 mm) excimer beam ablates through conjunctiva and external sclera until penetrating the outer wall of Schlemm's canal, at which time brisk egress of fluid is noted. The conjunctiva is allowed to retract, and a conjunctival bleb is formed. A single suture is used to close the conjunctival defect. Intraocular pressure in the rabbit eye was decreased from 10.0 ± 1.8 to 4.9 ± 1.8 mmHg immediately after surgery (p < 0.0001). Histology revealed a partial thickness, smooth‐walled ablation consistent with a sinusotomy. This procedure is minimally invasive and may be useful for management of glaucoma, particularly when a substantial component of the impediment to aqueous outflow is external to the trabecular meshwork. 1994 Institution Acta Ophthalmologica Scandinavica

AB - Abstract. Successful surgical management of glaucoma is limited as a consequence of undesired fibroblastic response of episcleral tissues. In 10 rabbit and three human eye bank eyes, we have performed a modified sinusotomy procedure using the 193‐nm excimer laser. The technique is minimally invasive. Conjunctiva is pulled over the corneoscleral limbus, and a slit‐shaped (1times2 mm) excimer beam ablates through conjunctiva and external sclera until penetrating the outer wall of Schlemm's canal, at which time brisk egress of fluid is noted. The conjunctiva is allowed to retract, and a conjunctival bleb is formed. A single suture is used to close the conjunctival defect. Intraocular pressure in the rabbit eye was decreased from 10.0 ± 1.8 to 4.9 ± 1.8 mmHg immediately after surgery (p < 0.0001). Histology revealed a partial thickness, smooth‐walled ablation consistent with a sinusotomy. This procedure is minimally invasive and may be useful for management of glaucoma, particularly when a substantial component of the impediment to aqueous outflow is external to the trabecular meshwork. 1994 Institution Acta Ophthalmologica Scandinavica

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Transconjunctival sinusotomy using the 193‐nm excimer laser

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Keywords

ASJC Scopus subject areas

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