Tracer permeabilities underestimate transmembrane solute flux under a concentration gradient

R. A. Meyer; E. C. Hills; M. H. Friedman

doi:10.1016/S0376-7388(00)82313-3

Tracer permeabilities underestimate transmembrane solute flux under a concentration gradient

R. A. Meyer, E. C. Hills, M. H. Friedman

School of Medicine

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The measured flux of sucrose across Cuprophan dialysis membrane in the presence of a concentration gradient is significantly greater than the flux predicted from radioactive tracer permeabilities measured in the absence of a concentration gradient. The difference can be explained if the membrane is heteroporous. Similar results are expected for other heterogeneous biological or artificial membranes.

Original language	English (US)
Pages (from-to)	247-253
Number of pages	7
Journal	Journal of Membrane Science
Volume	8
Issue number	3
DOIs	https://doi.org/10.1016/S0376-7388(00)82313-3
State	Published - 1981

ASJC Scopus subject areas

Biochemistry
Materials Science(all)
Physical and Theoretical Chemistry
Filtration and Separation

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10.1016/S0376-7388(00)82313-3

Cite this

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title = "Tracer permeabilities underestimate transmembrane solute flux under a concentration gradient",

abstract = "The measured flux of sucrose across Cuprophan dialysis membrane in the presence of a concentration gradient is significantly greater than the flux predicted from radioactive tracer permeabilities measured in the absence of a concentration gradient. The difference can be explained if the membrane is heteroporous. Similar results are expected for other heterogeneous biological or artificial membranes.",

author = "Meyer, {R. A.} and Hills, {E. C.} and Friedman, {M. H.}",

note = "Funding Information: All experiments were carried out using an NIH reference sample of Cuprophan 150PM, kindly supplied to us by J.K. Smith and F.F. Holland, Gulf South Research Institute, New Orleans, LA. The authors also appreciate the many contributions of E.A. Michelson. This work was supported in part by the Department of the Navy under Contract No. N00024-78-C-5384.",

year = "1981",

doi = "10.1016/S0376-7388(00)82313-3",

language = "English (US)",

volume = "8",

pages = "247--253",

journal = "Journal of Membrane Science",

issn = "0376-7388",

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TY - JOUR

T1 - Tracer permeabilities underestimate transmembrane solute flux under a concentration gradient

AU - Meyer, R. A.

AU - Hills, E. C.

AU - Friedman, M. H.

N1 - Funding Information: All experiments were carried out using an NIH reference sample of Cuprophan 150PM, kindly supplied to us by J.K. Smith and F.F. Holland, Gulf South Research Institute, New Orleans, LA. The authors also appreciate the many contributions of E.A. Michelson. This work was supported in part by the Department of the Navy under Contract No. N00024-78-C-5384.

PY - 1981

Y1 - 1981

N2 - The measured flux of sucrose across Cuprophan dialysis membrane in the presence of a concentration gradient is significantly greater than the flux predicted from radioactive tracer permeabilities measured in the absence of a concentration gradient. The difference can be explained if the membrane is heteroporous. Similar results are expected for other heterogeneous biological or artificial membranes.

AB - The measured flux of sucrose across Cuprophan dialysis membrane in the presence of a concentration gradient is significantly greater than the flux predicted from radioactive tracer permeabilities measured in the absence of a concentration gradient. The difference can be explained if the membrane is heteroporous. Similar results are expected for other heterogeneous biological or artificial membranes.

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U2 - 10.1016/S0376-7388(00)82313-3

DO - 10.1016/S0376-7388(00)82313-3

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AN - SCOPUS:0019583605

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VL - 8

SP - 247

EP - 253

JO - Journal of Membrane Science

JF - Journal of Membrane Science

IS - 3

ER -

Tracer permeabilities underestimate transmembrane solute flux under a concentration gradient

Abstract

ASJC Scopus subject areas

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