Toxicity Testing in the 21st Century: Approaches to Implementation

Thomas Hartung; Martin L Stephens

doi:10.1016/B978-0-12-386454-3.00679-5

Toxicity Testing in the 21st Century: Approaches to Implementation

Thomas Hartung, Martin L Stephens

Bloomberg School of Public Health

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

A number of activities have started to implement the 2007 National Research Council report on "Toxicity Testing in the 21st Century - A Vision and a Strategy." These activities aim to embrace modern technologies and base safety assessments on the mode of actions of toxicants. Molecularly defined pathways of toxicity are at the center of the approach, collectively forming the Human Toxome.

Original language	English (US)
Title of host publication	Encyclopedia of Toxicology
Subtitle of host publication	Third Edition
Publisher	Elsevier
Pages	673-675
Number of pages	3
ISBN (Electronic)	9780123864543
ISBN (Print)	9780123864550
DOIs	https://doi.org/10.1016/B978-0-12-386454-3.00679-5
State	Published - Jan 1 2014

Keywords

3Rs
Alternative methods
Evidence-based toxicology
High-throughput testing
Human toxome
Omics technologies
Pathways of toxicity
Regulatory toxicology

ASJC Scopus subject areas

Medicine(all)

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10.1016/B978-0-12-386454-3.00679-5

Cite this

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AB - A number of activities have started to implement the 2007 National Research Council report on "Toxicity Testing in the 21st Century - A Vision and a Strategy." These activities aim to embrace modern technologies and base safety assessments on the mode of actions of toxicants. Molecularly defined pathways of toxicity are at the center of the approach, collectively forming the Human Toxome.

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KW - Human toxome

KW - Omics technologies

KW - Pathways of toxicity

KW - Regulatory toxicology

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PB - Elsevier

ER -

Toxicity Testing in the 21st Century: Approaches to Implementation

Abstract

Keywords

ASJC Scopus subject areas

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