Topoisomerase II and the response to antileukemic therapy

Scott H. Kaufmann, Steven D. Gore, Carole B. Miller, Richard J. Jones, Leonard A. Zwelling, Erasmus Schneider, Philip J. Burke, Judith E. Karp

Research output: Contribution to journalReview articlepeer-review

26 Scopus citations


A number of recent studies have investigated the expression of topoisomerase II in clinical leukemia specimens. Here we outline the rationale for these studies, identify potential pitfalls, summarize recent results, and discuss unanswered questions in this area.

Original languageEnglish (US)
Pages (from-to)217-237
Number of pages21
JournalLeukemia and Lymphoma
Issue number3-4
StatePublished - 1998


  • Antileukemic therapy
  • Response to therapy
  • Topoisomerase II

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research


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