Topical amphotericin B in combination with standard therapy for severe necrotizing skin and soft-tissue mucormycosis in an infant with bilineal leukemia: Case report and review

Maria C. Di Pentima; Shannon Chan; Jonathan Powell; Joseph A. Napoli; Andrew W. Walter; Thomas J. Walsh

doi:10.1097/MPH.0000000000000166

Topical amphotericin B in combination with standard therapy for severe necrotizing skin and soft-tissue mucormycosis in an infant with bilineal leukemia: Case report and review

Maria C. Di Pentima, Shannon Chan, Jonathan Powell, Joseph A. Napoli, Andrew W. Walter, Thomas J. Walsh

Research output: Contribution to journal › Article › peer-review

Abstract

During chemotherapy for bilineal leukemia, a 6-month-old infant presented with a necrotizing skin and soft-tissue infection of the chest wall due to Rhizopus sp. Successful outcome was achieved by systemically administered liposomal amphotericin B and local wound control with the novel administration of topical deoxycholate amphotericin B and surgical resection.

Original language	English (US)
Journal	Journal of Pediatric Hematology/Oncology
DOIs	https://doi.org/10.1097/MPH.0000000000000166
State	Accepted/In press - Apr 11 2014
Externally published	Yes

ASJC Scopus subject areas

Hematology
Oncology
Pediatrics, Perinatology, and Child Health

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10.1097/MPH.0000000000000166

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Di Pentima, M. C., Chan, S., Powell, J., Napoli, J. A., Walter, A. W., & Walsh, T. J. (Accepted/In press). Topical amphotericin B in combination with standard therapy for severe necrotizing skin and soft-tissue mucormycosis in an infant with bilineal leukemia: Case report and review. Journal of Pediatric Hematology/Oncology. https://doi.org/10.1097/MPH.0000000000000166

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abstract = "During chemotherapy for bilineal leukemia, a 6-month-old infant presented with a necrotizing skin and soft-tissue infection of the chest wall due to Rhizopus sp. Successful outcome was achieved by systemically administered liposomal amphotericin B and local wound control with the novel administration of topical deoxycholate amphotericin B and surgical resection.",

author = "{Di Pentima}, {Maria C.} and Shannon Chan and Jonathan Powell and Napoli, {Joseph A.} and Walter, {Andrew W.} and Walsh, {Thomas J.}",

year = "2014",

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doi = "10.1097/MPH.0000000000000166",

language = "English (US)",

journal = "Journal of Pediatric Hematology/Oncology",

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T1 - Topical amphotericin B in combination with standard therapy for severe necrotizing skin and soft-tissue mucormycosis in an infant with bilineal leukemia

T2 - Case report and review

AU - Di Pentima, Maria C.

AU - Chan, Shannon

AU - Powell, Jonathan

AU - Napoli, Joseph A.

AU - Walter, Andrew W.

AU - Walsh, Thomas J.

PY - 2014/4/11

Y1 - 2014/4/11

N2 - During chemotherapy for bilineal leukemia, a 6-month-old infant presented with a necrotizing skin and soft-tissue infection of the chest wall due to Rhizopus sp. Successful outcome was achieved by systemically administered liposomal amphotericin B and local wound control with the novel administration of topical deoxycholate amphotericin B and surgical resection.

AB - During chemotherapy for bilineal leukemia, a 6-month-old infant presented with a necrotizing skin and soft-tissue infection of the chest wall due to Rhizopus sp. Successful outcome was achieved by systemically administered liposomal amphotericin B and local wound control with the novel administration of topical deoxycholate amphotericin B and surgical resection.

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Topical amphotericin B in combination with standard therapy for severe necrotizing skin and soft-tissue mucormycosis in an infant with bilineal leukemia: Case report and review

Abstract

ASJC Scopus subject areas

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