Tobacco-alcohol amblyopia: A proposed biochemical basis for pathogenesis

Chi V. Dang

doi:10.1016/0306-9877(81)90122-5

Tobacco-alcohol amblyopia: A proposed biochemical basis for pathogenesis

Chi V. Dang

School of Medicine

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Tobacco-alcohol or nutritional amblyopia is a rare disorder of decreased central vision associated with nutritional deficiencies and tobacco smoking. Although folate deficiency is common in patients with tobacco-alcohol amblyopia, the role of folic acid in this disorder has been underplayed. The role of cyanide from tobacco smoke, folate and other dietary deficiencies will be reviewed. A new model of the pathogenesis of tobacco-alcohol amblyopia is proposed based on the presumptive alteration of methionine and S-adenosyl-L-methionine metabolism.

Original language	English (US)
Pages (from-to)	1317-1328
Number of pages	12
Journal	Medical Hypotheses
Volume	7
Issue number	11
DOIs	https://doi.org/10.1016/0306-9877(81)90122-5
State	Published - 1981

ASJC Scopus subject areas

Developmental Biology
Medicine(all)
Drug Discovery

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abstract = "Tobacco-alcohol or nutritional amblyopia is a rare disorder of decreased central vision associated with nutritional deficiencies and tobacco smoking. Although folate deficiency is common in patients with tobacco-alcohol amblyopia, the role of folic acid in this disorder has been underplayed. The role of cyanide from tobacco smoke, folate and other dietary deficiencies will be reviewed. A new model of the pathogenesis of tobacco-alcohol amblyopia is proposed based on the presumptive alteration of methionine and S-adenosyl-L-methionine metabolism.",

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PY - 1981

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AB - Tobacco-alcohol or nutritional amblyopia is a rare disorder of decreased central vision associated with nutritional deficiencies and tobacco smoking. Although folate deficiency is common in patients with tobacco-alcohol amblyopia, the role of folic acid in this disorder has been underplayed. The role of cyanide from tobacco smoke, folate and other dietary deficiencies will be reviewed. A new model of the pathogenesis of tobacco-alcohol amblyopia is proposed based on the presumptive alteration of methionine and S-adenosyl-L-methionine metabolism.

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Tobacco-alcohol amblyopia: A proposed biochemical basis for pathogenesis

Abstract

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