Time to Relax: Mechanical Stress Release Guides Stem Cell Responses

Sven D. Sommerfeld; Jennifer H. Elisseeff

doi:10.1016/j.stem.2016.01.020

Time to Relax: Mechanical Stress Release Guides Stem Cell Responses

Sven D. Sommerfeld, Jennifer H. Elisseeff

School of Medicine

Research output: Contribution to journal › Short survey › peer-review

10 Scopus citations

Abstract

Stem cells integrate spatiotemporal cues, including the mechanical properties of their microenvironment, into their fate decisions. Chaudhuri et al. (2015) show that the ability of the extracellular matrix to dissipate cell-induced forces, referred to as stress-relaxation, is a key mechanical signal influencing stem cell fate and function.

Original language	English (US)
Pages (from-to)	166-167
Number of pages	2
Journal	Cell stem cell
Volume	18
Issue number	2
DOIs	https://doi.org/10.1016/j.stem.2016.01.020
State	Published - Feb 4 2016

ASJC Scopus subject areas

Molecular Medicine
Genetics
Cell Biology

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10.1016/j.stem.2016.01.020

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title = "Time to Relax: Mechanical Stress Release Guides Stem Cell Responses",

abstract = "Stem cells integrate spatiotemporal cues, including the mechanical properties of their microenvironment, into their fate decisions. Chaudhuri et al. (2015) show that the ability of the extracellular matrix to dissipate cell-induced forces, referred to as stress-relaxation, is a key mechanical signal influencing stem cell fate and function.",

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AU - Sommerfeld, Sven D.

AU - Elisseeff, Jennifer H.

PY - 2016/2/4

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N2 - Stem cells integrate spatiotemporal cues, including the mechanical properties of their microenvironment, into their fate decisions. Chaudhuri et al. (2015) show that the ability of the extracellular matrix to dissipate cell-induced forces, referred to as stress-relaxation, is a key mechanical signal influencing stem cell fate and function.

AB - Stem cells integrate spatiotemporal cues, including the mechanical properties of their microenvironment, into their fate decisions. Chaudhuri et al. (2015) show that the ability of the extracellular matrix to dissipate cell-induced forces, referred to as stress-relaxation, is a key mechanical signal influencing stem cell fate and function.

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JO - Cell stem cell

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Time to Relax: Mechanical Stress Release Guides Stem Cell Responses

Abstract

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