Thrombosis of the portal vein following splenectomy for myeloid metaplasia

P. J. Broe, C. L. Conley, J. L. Cameron

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58 Scopus citations


The records of 28 patients undergoing splenectomy for myeloid metaplasia were reviewed. Portal and mesenteric venous thrombosis was proved or suspected in five patients. The time interval between splenectomy and portal and mesenteric venous thrombosis varied from six days to three years. The incidental postmortem finding of portal vein thrombosis in one patient suggest that the incidence may be greater than clinically appreciated and may, at times, by asymptomatic. Postsplenectomy thrombocytosis was not found to be a significant risk factor, occurring in only one of the five patients in whom portal vein thrombosis developed. Recommendations for prevention include ligation of the splenic vein close to its junction with the inferior mesenteric vein at the time of splenectomy. In addition, prophylactic anticoagulation therapy or the use of antiplatelet drug therapy postoperatively, or both, should be considered.

Original languageEnglish (US)
Pages (from-to)488-492
Number of pages5
JournalSurgery Gynecology and Obstetrics
Issue number4
StatePublished - Jan 1 1981

ASJC Scopus subject areas

  • Surgery
  • Obstetrics and Gynecology


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