Thromboprophylaxis across orthopaedic surgery: Bibliometric analysis of the most cited articles

Anil Sedani, Ramakanth Yakkanti, Paul Allegra, Lavi Mattingly, Amiethab Aiyer

Research output: Contribution to journalArticlepeer-review


Purpose: One of the most common adverse events after orthopaedic surgery, with a potential for subsequent serious morbidity and mortality is venous thromboembolism (VTE). Bibliometric analysis has been performed regarding many topics and across orthopaedics. As DVT prophylaxis is a major component of both orthopaedic surgery considerations and research, a bibliometric analysis in this area would prove beneficial in not only in understanding the research done in the field thus far, but would also direct future research efforts. Methods: The Web of Science (WoS) database from the Institute of Scientific Information (ISI) was used to compile articles for bibliometric analysis using Boolean search: ((Orthopaedic∗ OR Orthopaedic∗) AND (thromboprophylaxis OR Thromboembolism OR Deep vein thrombosis OR thrombus OR embolism OR anticoagulation OR Embolus OR prophylaxis)). Results: The Top 100 cited articles included in the final list generated a total of 21,099 citations. The highest cited article was Prevention of venous thromboembolism by Geerts et al. published in Chest, which had a total of 2802 on WoS, and a calculated citation density of 215.54 of citations/years since publication. Comparing the overall citation against the year of publication there was a slight positive trend favoring more recent publications (R-value: 0.142; adjusted R-squared: 0.01; p = 0.16). Analysis of an articles Level of Evidence (LOE), 17 were grade with a level of I. Conclusions: Orthopaedic thromboprophylaxis is an ever-changing field that is at the forefront of orthopaedic literature. The significant trend favoring high quality research within orthopaedic thromboprophylaxis demonstrates the importance of this topic and there was a need for a guide to best understand the evolution of DVT prophylaxis.

Original languageEnglish (US)
Pages (from-to)157-167
Number of pages11
JournalJournal of Clinical Orthopaedics and Trauma
StatePublished - May 2021
Externally publishedYes


  • Anticoagulation
  • Bibliometric analysis
  • Deep vein thrombosis
  • Pulmonary embolism
  • Venous thromboprophylaxis

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine


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