Abstract
Purpose: To evaluate the use of percutaneous transcatheter thrombolysis in the treatment of thrombosis due to radial artery cannulation. Methods and Results: Seven patients (4 women; age range 41-62 years) with symptomatic cannulation-induced thrombosis and failure to improve after systemic anticoagulation underwent 8 catheter-directed thrombolytic infusions at our institution over a 3-year period. Access was either antegrade through the brachial artery or retrograde through the femoral artery. Thrombolytic infusions with urokinase began 2 to 12 days (average 6) after removal of the radial artery catheter. The thrombolytic infusion was successful in 5 of 7 patients based on angiographic flow restoration with <20% residual thrombus and significant clinical improvement in the ischemia. Conclusions: When systemic anticoagulation has failed, percutaneous catheter-directed thrombolytic infusion appears to be effective in the treatment of most patients with severe ischemic hand symptoms due to thrombosis after radial artery cannulation.
Original language | English (US) |
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Pages (from-to) | 590-594 |
Number of pages | 5 |
Journal | Journal of Endovascular Therapy |
Volume | 10 |
Issue number | 3 |
DOIs | |
State | Published - Jun 2003 |
Externally published | Yes |
Keywords
- Catheterization
- Complications
- Hand ischemia
- Iatrogenic injury
- Radial artery
- Thrombolysis
- Thrombosis
- Urokinase
ASJC Scopus subject areas
- Surgery
- Radiology Nuclear Medicine and imaging
- Cardiology and Cardiovascular Medicine