Three minor new compounds from the aerial parts of Leonurus japonicus

Wei Mao Zhong; Zhao Meng Cui; Zhi Ke Liu; Yan Yang; Da Rong Wu; Shao Hua Liu; Hui Long; Han Dong Sun; Yong Jun Dang; Wei Lie Xiao

doi:10.1016/j.cclet.2015.05.004

Three minor new compounds from the aerial parts of Leonurus japonicus

Wei Mao Zhong, Zhao Meng Cui, Zhi Ke Liu, Yan Yang, Da Rong Wu, Shao Hua Liu, Hui Long, Han Dong Sun, Yong Jun Dang, Wei Lie Xiao

School of Medicine

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Abstract Phytochemical investigation of the aerial parts of Leonurus japonicus led to the isolation of one new labdane diterpenoid, leojaponin D (1) and two new ionone derivatives, leojaponones A and B (2 and 3), together with seven known diterpenoids (4-10). Their structures were elucidated by extensive 1D and 2D NMR spectroscopic data and by comparison with data reported in the literature. Selected isolates were evaluated their effects on Jurkat IL2 secretion.

Original language	English (US)
Article number	3308
Pages (from-to)	1000-1003
Number of pages	4
Journal	Chinese Chemical Letters
Volume	26
Issue number	8
DOIs	https://doi.org/10.1016/j.cclet.2015.05.004
State	Published - Aug 11 2015

Keywords

Diterpenoid
Ionone derivative
Jurkat IL2 secretion
Leonurus japonicus

ASJC Scopus subject areas

General Chemistry

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10.1016/j.cclet.2015.05.004

Cite this

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title = "Three minor new compounds from the aerial parts of Leonurus japonicus",

abstract = "Abstract Phytochemical investigation of the aerial parts of Leonurus japonicus led to the isolation of one new labdane diterpenoid, leojaponin D (1) and two new ionone derivatives, leojaponones A and B (2 and 3), together with seven known diterpenoids (4-10). Their structures were elucidated by extensive 1D and 2D NMR spectroscopic data and by comparison with data reported in the literature. Selected isolates were evaluated their effects on Jurkat IL2 secretion.",

keywords = "Diterpenoid, Ionone derivative, Jurkat IL2 secretion, Leonurus japonicus",

author = "Zhong, {Wei Mao} and Cui, {Zhao Meng} and Liu, {Zhi Ke} and Yan Yang and Wu, {Da Rong} and Liu, {Shao Hua} and Hui Long and Sun, {Han Dong} and Dang, {Yong Jun} and Xiao, {Wei Lie}",

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month = aug,

day = "11",

doi = "10.1016/j.cclet.2015.05.004",

language = "English (US)",

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T1 - Three minor new compounds from the aerial parts of Leonurus japonicus

AU - Zhong, Wei Mao

AU - Cui, Zhao Meng

AU - Liu, Zhi Ke

AU - Yang, Yan

AU - Wu, Da Rong

AU - Liu, Shao Hua

AU - Long, Hui

AU - Sun, Han Dong

AU - Dang, Yong Jun

AU - Xiao, Wei Lie

PY - 2015/8/11

Y1 - 2015/8/11

N2 - Abstract Phytochemical investigation of the aerial parts of Leonurus japonicus led to the isolation of one new labdane diterpenoid, leojaponin D (1) and two new ionone derivatives, leojaponones A and B (2 and 3), together with seven known diterpenoids (4-10). Their structures were elucidated by extensive 1D and 2D NMR spectroscopic data and by comparison with data reported in the literature. Selected isolates were evaluated their effects on Jurkat IL2 secretion.

AB - Abstract Phytochemical investigation of the aerial parts of Leonurus japonicus led to the isolation of one new labdane diterpenoid, leojaponin D (1) and two new ionone derivatives, leojaponones A and B (2 and 3), together with seven known diterpenoids (4-10). Their structures were elucidated by extensive 1D and 2D NMR spectroscopic data and by comparison with data reported in the literature. Selected isolates were evaluated their effects on Jurkat IL2 secretion.

KW - Diterpenoid

KW - Ionone derivative

KW - Jurkat IL2 secretion

KW - Leonurus japonicus

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DO - 10.1016/j.cclet.2015.05.004

M3 - Article

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JO - Chinese Chemical Letters

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Three minor new compounds from the aerial parts of Leonurus japonicus

Abstract

Keywords

ASJC Scopus subject areas

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