Three-dimensional true-FISP imaging of the coronary arteries: Improved contrast with T2-preparation

Steven M. Shea, Vibhas S. Deshpande, Yiu Cho Chung, Debiao Li

Research output: Contribution to journalArticlepeer-review

85 Scopus citations


Purpose: To evaluate the effectiveness of a T2-magnetization preparation scheme for improving coronary artery imaging with true fast imaging with steady-state precession (True-FISP). Materials and Methods: Simulations were performed to compare the blood-myocardium signal difference with no T2-preparation to that with various T2-preparation times (24, 40, and 60 msec) using an electrocardiogram (ECG)-triggered, segmented True-FISP acquisition. Seven volunteers were imaged to evaluate the effectiveness of T2-preparation for coronary artery delineation using True-FISP and to optimize the T2-preparation time. Results: Simulations showed that T2-preparation improved the signal difference between blood and myocardium over that without T2-preparation. The optimal T2 preparation time was determined to be 40 msec. In volunteer studies, a T2-preparation time of 40 msec provided a significant improvement in contrast-to-noise ratio (CNR) between the coronary arteries and myocardium over that without T2-preparation. It also showed a significant improvement in visualizing the distal portions of the coronary arteries. Conclusion: T2-preparation improves coronary artery delineation with True-FISP.

Original languageEnglish (US)
Pages (from-to)597-602
Number of pages6
JournalJournal of Magnetic Resonance Imaging
Issue number5
StatePublished - 2002
Externally publishedYes


  • Coronary artery imaging
  • Fast imaging
  • MR angiography
  • Magnetic resonance imaging
  • Magnetization-prepared conrast

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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