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Three-dimensional chemical patterns for cellular self-organization

Research output: Contribution to journal › Article › peer-review

Abstract

Falling into line: A method for the precise generation of durable 3D chemical patterns within stationary media was used to direct the chemotactic self-organization of living cells. A container with carefully positioned slits, through which a chemoattractant (yellow) can diffuse, controls the self-organization of Escherichia coli cells (green ellipsoids) expressing green fluorescent protein into a helical pattern (see fluorescence images).

Original languageEnglish (US)
Pages (from-to)2549-2553
Number of pages5
JournalAngewandte Chemie - International Edition
Volume50
Issue number11
DOIs
StatePublished - Mar 7 2011

Keywords

  • chemical patterning
  • chemotaxis
  • drug delivery
  • self-assembly
  • tissue engineering

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry

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