Therapeutic hypothermia for traumatic brain injury and spinal cord injury

Shamir Haji; Geoffrey Ling

doi:10.1007/978-3-319-40208-6_25

Therapeutic hypothermia for traumatic brain injury and spinal cord injury

Shamir Haji, Geoffrey Ling

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Induced hypothermia or targeted temperature management has been studied as a potential therapy for improving outcome following traumatic brain injury (TBI) and to a lesser extent, spinal cord injury (SCI). Hypothermia has been clearly demonstrated to improve clinical outcome following cardiac arrest. Preclinical TBI models have shown efficacy. Unfortunately, to date, this is not true for clinical moderate to severe TBI in humans. The same is true for spinal cord injury (SCI). As a result, there is insufficient evidence to support the routine use of induced hypothermia for improving outcome following TBI or SCI. The one clinical condition for which induced hypothermia may be useful is reducing elevated intracranial pressure (ICP) that is recalcitrant to standard medical therapy.

Original language	English (US)
Title of host publication	Neurotrauma Management for the Severely Injured Polytrauma Patient
Publisher	Springer International Publishing
Pages	247-252
Number of pages	6
ISBN (Electronic)	9783319402086
ISBN (Print)	9783319402062
DOIs	https://doi.org/10.1007/978-3-319-40208-6_25
State	Published - Jan 1 2017

Keywords

Cardiac arrest
Decompression
Hypothermia
Intracranial pressure (ICP)
Neuroinflammation
Pediatric
Spinal cord injury (SCI)
Targeted temperature management
Traumatic brain injury (TBI)

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1007/978-3-319-40208-6_25

Cite this

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Therapeutic hypothermia for traumatic brain injury and spinal cord injury

Abstract

Keywords

ASJC Scopus subject areas

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