TY - JOUR
T1 - The veterans affairs saint louis university mental status exam (SLUMS Exam) and the mini-mental status exam as predictors of mortality and institutionalization
AU - Cruz-Oliver, D. M.
AU - Malmstrom, T. K.
AU - Allen, C. M.
AU - Tumosa, N.
AU - Morley, J. E.
N1 - Funding Information:
Acknowledgements: The authors thank study participants and acknowledge support from the Department of Internal Medicine Division of Geriatric Medicine, Saint Louis University School of Medicine and the Geriatric Research, Education and Clinical Center (GRECC) at Department of Veterans Affairs in St. Louis, MO. They also thank Asad Riaz, MD for assistance with data collection.
PY - 2012/7
Y1 - 2012/7
N2 - Objective: To evaluate predictive validity of cognitive dysfunction of the Saint Louis University Mental Status (SLUMS) exam or Mini-Mental State Exam (MMSE) for institutionalization and mortality after 7.5-years. Design: Longitudinal study. Setting: Geriatric Research, Education and Clinical Center Veterans Affairs Hospital St. Louis, MO. Participants: Patients (N=705) were screened for cognitive dysfunction in 2003 using the SLUMS exam and MMSE, and mortality and institutionalization up to 7.5-years later were evaluated as outcome measures. Measurement: The associations between outcome measures and MMSE and SLUMS exam total scores, and cognitive status were examined using Kaplan-Meier curves and Cox proportional-hazards regression. Results: Five hundred thirty-three charts were reviewed, 176/533(33%) patients had died and 31/526 (6%) were institutionalized during 7.5-year follow-up period. All subjects were male with a mean age of 75 years and most had high school education or greater (71%). MMSE dementia, SLUMS dementia (ps<.001) and MCI (p<.05) groups had significantly lower survival rates than normal cognition group in the Kaplan-Meier curves. Scores classified as dementia on SLUMS (HR=2.4, 95% CI 1.6-3.7; p <.001) or MMSE (HR=2.3, 95% CI 1.5-3.6; p <.001) both predicted mortality and, also, institutionalization (SLUMS: HR=3.5, 95% CI 1.3-9.1; p <.01; MMSE: HR=3.8, 95% CI 1.6-9.0; p <.001) after adjustment for covariates. Unadjusted SLUMS exam MCI predicted morality (HR=1.5, 95% CI 1.1-2.2; p <.019) but not institutionalization. Conclusion: The SLUMS exam and MMSE both predict mortality and institutionalization for male patients screened as positive for dementia. The Journal of Nutrition, Health and Aging
AB - Objective: To evaluate predictive validity of cognitive dysfunction of the Saint Louis University Mental Status (SLUMS) exam or Mini-Mental State Exam (MMSE) for institutionalization and mortality after 7.5-years. Design: Longitudinal study. Setting: Geriatric Research, Education and Clinical Center Veterans Affairs Hospital St. Louis, MO. Participants: Patients (N=705) were screened for cognitive dysfunction in 2003 using the SLUMS exam and MMSE, and mortality and institutionalization up to 7.5-years later were evaluated as outcome measures. Measurement: The associations between outcome measures and MMSE and SLUMS exam total scores, and cognitive status were examined using Kaplan-Meier curves and Cox proportional-hazards regression. Results: Five hundred thirty-three charts were reviewed, 176/533(33%) patients had died and 31/526 (6%) were institutionalized during 7.5-year follow-up period. All subjects were male with a mean age of 75 years and most had high school education or greater (71%). MMSE dementia, SLUMS dementia (ps<.001) and MCI (p<.05) groups had significantly lower survival rates than normal cognition group in the Kaplan-Meier curves. Scores classified as dementia on SLUMS (HR=2.4, 95% CI 1.6-3.7; p <.001) or MMSE (HR=2.3, 95% CI 1.5-3.6; p <.001) both predicted mortality and, also, institutionalization (SLUMS: HR=3.5, 95% CI 1.3-9.1; p <.01; MMSE: HR=3.8, 95% CI 1.6-9.0; p <.001) after adjustment for covariates. Unadjusted SLUMS exam MCI predicted morality (HR=1.5, 95% CI 1.1-2.2; p <.019) but not institutionalization. Conclusion: The SLUMS exam and MMSE both predict mortality and institutionalization for male patients screened as positive for dementia. The Journal of Nutrition, Health and Aging
KW - Dementia
KW - Institutionalization
KW - MMSE
KW - Mild cognitive impairment
KW - Mortality
KW - SLUMS exam
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U2 - 10.1007/s12603-012-0098-9
DO - 10.1007/s12603-012-0098-9
M3 - Article
C2 - 22836706
AN - SCOPUS:84867294036
SN - 1279-7707
VL - 16
SP - 636
EP - 641
JO - Journal of Nutrition, Health and Aging
JF - Journal of Nutrition, Health and Aging
IS - 7
ER -