The structure of a Cryptococcus neoformans polysaccharide motif recognized by protective antibodies: A combined NMR and MD study

Keyphrases

• Polysaccharide 100%
• Cryptococcus Neoformans 100%
• Protective Antibodies 100%
• Glucuronoxylomannan 80%
• Neoformans 40%
• Xylose 40%
• Glucuronic Acid 40%
• Mannan 40%
• MD Analysis 40%
• Phagocytosis 20%
• Deacetylation 20%
• Specific Monoclonal Antibodies 20%
• Fungal Pathogens 20%
• NMR Analysis 20%
• Virulence Factors 20%
• Glycoconjugates 20%
• Cryptococcal Meningitis 20%
• Cryptococcosis 20%
• Cryptococcus 20%
• Capsular Polysaccharide 20%
• Molecular Dynamics Simulation 20%
• High Flexibility 20%
• Repeating Unit 20%
• Fungal Cells 20%
• Intermolecular Interactions 20%
• J-coupling 20%
• NMR Experiments 20%
• Serotype A 20%
• Exopolysaccharide 20%
• Extended Structure 20%
• Polysaccharide Interactions 20%
• Coupling Values 20%
• Hexasaccharide 20%
• Polymer Support 20%
• Acetyl Esters 20%
• Structural Identity 20%

Immunology and Microbiology

• Monospecific Antibody 100%
• Cryptococcus neoformans 100%
• Spine 100%
• Monoclonal Antibody 50%
• Vaccine Efficacy 50%
• Infectious Agent 50%
• Phagocytosis 50%
• Serotype 50%
• Virulence Factor 50%
• Glycoconjugate 50%
• Meningitis 50%
• Fungal Cell 50%
• Intermolecular Interaction 50%

Biochemistry, Genetics and Molecular Biology

• Monospecific Antibody 100%
• Cryptococcus neoformans 100%
• Polysaccharide 100%
• Glucuronic Acid 28%
• Xylose 28%
• Mannan 28%
• Infectious Agent 14%
• Phagocytosis 14%
• Monoclonal Antibody 14%
• Virulence Factor 14%
• Glycoconjugate 14%
• Serotype 14%