The stress response after traumatic brain injury: Metabolic and hormonal aspects

Hervé Quintard, Carole Ichai, Jean Francois Payen

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


The pathophysiology of TBI can be considered as a dual insult composed of primary and secondary injuries. Growing experimental and clinical evidence suggests that disturbances of cerebral energy metabolism are a key factor in the pathogenesis of secondary cerebral damages. In addition, hormonal dysfunction after TBI, such as adrenal insuffi ciency, vasopressin, growth hormone, or thyrothropin defi ciency, can be associated with poor prognosis. A better understanding of energy metabolism and hormonal disturbances after TBI is necessary to improve the care management at the early phase of TBI.

Original languageEnglish (US)
Title of host publicationThe Stress Response of Critical Illness
Subtitle of host publicationMetabolic and Hormonal Aspects
PublisherSpringer International Publishing
Number of pages10
ISBN (Electronic)9783319276878
ISBN (Print)9783319276854
StatePublished - Jan 1 2016
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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