The stress response after traumatic brain injury: Metabolic and hormonal aspects

Hervé Quintard; Carole Ichai; Jean Francois Payen

doi:10.1007/978-3-319-27687-8_16

The stress response after traumatic brain injury: Metabolic and hormonal aspects

Hervé Quintard, Carole Ichai, Jean Francois Payen

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

The pathophysiology of TBI can be considered as a dual insult composed of primary and secondary injuries. Growing experimental and clinical evidence suggests that disturbances of cerebral energy metabolism are a key factor in the pathogenesis of secondary cerebral damages. In addition, hormonal dysfunction after TBI, such as adrenal insuffi ciency, vasopressin, growth hormone, or thyrothropin defi ciency, can be associated with poor prognosis. A better understanding of energy metabolism and hormonal disturbances after TBI is necessary to improve the care management at the early phase of TBI.

Original language	English (US)
Title of host publication	The Stress Response of Critical Illness
Subtitle of host publication	Metabolic and Hormonal Aspects
Publisher	Springer International Publishing
Pages	197-206
Number of pages	10
ISBN (Electronic)	9783319276878
ISBN (Print)	9783319276854
DOIs	https://doi.org/10.1007/978-3-319-27687-8_16
State	Published - Jan 1 2016
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

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10.1007/978-3-319-27687-8_16

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AU - Ichai, Carole

AU - Payen, Jean Francois

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AB - The pathophysiology of TBI can be considered as a dual insult composed of primary and secondary injuries. Growing experimental and clinical evidence suggests that disturbances of cerebral energy metabolism are a key factor in the pathogenesis of secondary cerebral damages. In addition, hormonal dysfunction after TBI, such as adrenal insuffi ciency, vasopressin, growth hormone, or thyrothropin defi ciency, can be associated with poor prognosis. A better understanding of energy metabolism and hormonal disturbances after TBI is necessary to improve the care management at the early phase of TBI.

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The stress response after traumatic brain injury: Metabolic and hormonal aspects

Abstract

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