The sonography of diffuse liver disease

W. W. Scott, P. J. Donovan, R. C. Sanders

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


The ultrasound diagnosis of diffuse liver disease is fraught with complexities and as a result many clinicans prefer routine liver biopsy. This invasive procedure, of course, has its own contraindications and complications. Additionally, the reliability of the biopsy diagnosis is predicated on the assumption that the fatty change or other heptocellular disease is uniformly distributed throughout the liver. Recently, as mentioned above, it has become more widely recognized that processes like fatty change are not always uniform. In such instances, the biopsy may grossly misrepresent the histologic situation in the majority of the liver. Hopefully in the future, ultrasound and other noninvasive procedures such as CT and radionuclide studies will offer effective alternatives for diagnosis of diffuse hepatic disease.

Original languageEnglish (US)
Pages (from-to)219-225
Number of pages7
JournalSeminars in Ultrasound
Issue number3
StatePublished - Jan 1 1981

ASJC Scopus subject areas

  • General Medicine


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