The second generation HRRT - A multi-centre scanner performance investigation

Vesna Sossi, Hugo W.A.M. De Jong, W. Craig Barker, Peter Bloomfield, Ziad Burbar, Marie Laure Camborde, Claude Comtat, Lars A. Eriksson, Sylvain Houle, David Keator, Christof Knöß, Roman Krais, Adriaan A. Lammertsma, Arman Rahmim, Mérence Sibomana, Mika Teräs, Christopher J. Thompson, Régine Trébossen, John Votaw, Matthew WalkerKlaus Wienhard, Dean F. Wong

Research output: Chapter in Book/Report/Conference proceedingConference contribution

80 Scopus citations


The high resolution research tomograph (HRRT) is one of the most complex existing Positron Emission Tomographs: it is the only human size scanner capable of decoding the depth of the γ-ray interaction in the crystal, using a lutetium LSO/LYSO phoswitch detector arrangement. In this study we determined basic scanner hardware characteristics, such as scanner data acquisition stability, and their variability across eleven centres. In addition a subset of the NEMA NU-2001 standards measurements was performed. We found (i) significant variability in the DOI decoding results between centres, (ii) a trend toward an increasing number of detected true coincident events as a function of elapsed time from scanner calibration likely due to a shifting energy spectrum, (iii) a count-rate dependent layer identification, (iv) scatter fraction ranging from ∼ 42% to 54% where the variability was partly related to the shifting of the energy spectrum, (v) sensitivity ranging from ∼ 5.5% to 6.5% across centres, (vi) resolution of ∼ (2.5mm)3, fairly consistent across centres, (vii) image quality which is very comparable to other scanners.

Original languageEnglish (US)
Title of host publication2005 IEEE Nuclear Science Symposium Conference Record -Nuclear Science Symposium and Medical Imaging Conference
Number of pages5
StatePublished - 2005
Externally publishedYes
EventNuclear Science Symposium Conference Record, 2005 IEEE - , Puerto Rico
Duration: Oct 23 2005Oct 29 2005

Publication series

NameIEEE Nuclear Science Symposium Conference Record
ISSN (Print)1095-7863


OtherNuclear Science Symposium Conference Record, 2005 IEEE
Country/TerritoryPuerto Rico


  • Depth of interaction
  • High resolution research tomograph
  • PET
  • Performance study
  • Positron emission tomography
  • Resolution
  • Scatter fraction
  • Sensitivity
  • Stability

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging


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