The second generation HRRT - A multi-centre scanner performance investigation

Vesna Sossi; Hugo W.A.M. De Jong; W. Craig Barker; Peter Bloomfield; Ziad Burbar; Marie Laure Camborde; Claude Comtat; Lars A. Eriksson; Sylvain Houle; David Keator; Christof Knöß; Roman Krais; Adriaan A. Lammertsma; Arman Rahmim; Mérence Sibomana; Mika Teräs; Christopher J. Thompson; Régine Trébossen; John Votaw; Matthew Walker; Klaus Wienhard; Dean F. Wong

doi:10.1109/NSSMIC.2005.1596770

The second generation HRRT - A multi-centre scanner performance investigation

Vesna Sossi, Hugo W.A.M. De Jong, W. Craig Barker, Peter Bloomfield, Ziad Burbar, Marie Laure Camborde, Claude Comtat, Lars A. Eriksson, Sylvain Houle, David Keator, Christof Knöß, Roman Krais, Adriaan A. Lammertsma, Arman Rahmim, Mérence Sibomana, Mika Teräs, Christopher J. Thompson, Régine Trébossen, John Votaw, Matthew WalkerKlaus Wienhard, Dean F. Wong

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

80 Scopus citations

Abstract

The high resolution research tomograph (HRRT) is one of the most complex existing Positron Emission Tomographs: it is the only human size scanner capable of decoding the depth of the γ-ray interaction in the crystal, using a lutetium LSO/LYSO phoswitch detector arrangement. In this study we determined basic scanner hardware characteristics, such as scanner data acquisition stability, and their variability across eleven centres. In addition a subset of the NEMA NU-2001 standards measurements was performed. We found (i) significant variability in the DOI decoding results between centres, (ii) a trend toward an increasing number of detected true coincident events as a function of elapsed time from scanner calibration likely due to a shifting energy spectrum, (iii) a count-rate dependent layer identification, (iv) scatter fraction ranging from ∼ 42% to 54% where the variability was partly related to the shifting of the energy spectrum, (v) sensitivity ranging from ∼ 5.5% to 6.5% across centres, (vi) resolution of ∼ (2.5mm)³, fairly consistent across centres, (vii) image quality which is very comparable to other scanners.

Original language	English (US)
Title of host publication	2005 IEEE Nuclear Science Symposium Conference Record -Nuclear Science Symposium and Medical Imaging Conference
Pages	2195-2199
Number of pages	5
DOIs	https://doi.org/10.1109/NSSMIC.2005.1596770
State	Published - 2005
Externally published	Yes
Event	Nuclear Science Symposium Conference Record, 2005 IEEE - , Puerto Rico Duration: Oct 23 2005 → Oct 29 2005

Publication series

Name	IEEE Nuclear Science Symposium Conference Record
Volume	4
ISSN (Print)	1095-7863

Other

Other	Nuclear Science Symposium Conference Record, 2005 IEEE
Country/Territory	Puerto Rico
Period	10/23/05 → 10/29/05

Keywords

Depth of interaction
ECAT HRRT
High resolution research tomograph
PET
Performance study
Positron emission tomography
Resolution
Scatter fraction
Sensitivity
Stability

ASJC Scopus subject areas

Radiation
Nuclear and High Energy Physics
Radiology Nuclear Medicine and imaging

Access to Document

10.1109/NSSMIC.2005.1596770

Cite this

Sossi, V., De Jong, H. W. A. M., Barker, W. C., Bloomfield, P., Burbar, Z., Camborde, M. L., Comtat, C., Eriksson, L. A., Houle, S., Keator, D., Knöß, C., Krais, R., Lammertsma, A. A., Rahmim, A., Sibomana, M., Teräs, M., Thompson, C. J., Trébossen, R., Votaw, J., ... Wong, D. F. (2005). The second generation HRRT - A multi-centre scanner performance investigation. In 2005 IEEE Nuclear Science Symposium Conference Record -Nuclear Science Symposium and Medical Imaging Conference (pp. 2195-2199). Article 1596770 (IEEE Nuclear Science Symposium Conference Record; Vol. 4). https://doi.org/10.1109/NSSMIC.2005.1596770

The second generation HRRT - A multi-centre scanner performance investigation. / Sossi, Vesna; De Jong, Hugo W.A.M.; Barker, W. Craig et al.
2005 IEEE Nuclear Science Symposium Conference Record -Nuclear Science Symposium and Medical Imaging Conference. 2005. p. 2195-2199 1596770 (IEEE Nuclear Science Symposium Conference Record; Vol. 4).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Sossi, V, De Jong, HWAM, Barker, WC, Bloomfield, P, Burbar, Z, Camborde, ML, Comtat, C, Eriksson, LA, Houle, S, Keator, D, Knöß, C, Krais, R, Lammertsma, AA, Rahmim, A, Sibomana, M, Teräs, M, Thompson, CJ, Trébossen, R, Votaw, J, Walker, M, Wienhard, K & Wong, DF 2005, The second generation HRRT - A multi-centre scanner performance investigation. in 2005 IEEE Nuclear Science Symposium Conference Record -Nuclear Science Symposium and Medical Imaging Conference., 1596770, IEEE Nuclear Science Symposium Conference Record, vol. 4, pp. 2195-2199, Nuclear Science Symposium Conference Record, 2005 IEEE, Puerto Rico, 10/23/05. https://doi.org/10.1109/NSSMIC.2005.1596770

Sossi V, De Jong HWAM, Barker WC, Bloomfield P, Burbar Z, Camborde ML et al. The second generation HRRT - A multi-centre scanner performance investigation. In 2005 IEEE Nuclear Science Symposium Conference Record -Nuclear Science Symposium and Medical Imaging Conference. 2005. p. 2195-2199. 1596770. (IEEE Nuclear Science Symposium Conference Record). doi: 10.1109/NSSMIC.2005.1596770

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abstract = "The high resolution research tomograph (HRRT) is one of the most complex existing Positron Emission Tomographs: it is the only human size scanner capable of decoding the depth of the γ-ray interaction in the crystal, using a lutetium LSO/LYSO phoswitch detector arrangement. In this study we determined basic scanner hardware characteristics, such as scanner data acquisition stability, and their variability across eleven centres. In addition a subset of the NEMA NU-2001 standards measurements was performed. We found (i) significant variability in the DOI decoding results between centres, (ii) a trend toward an increasing number of detected true coincident events as a function of elapsed time from scanner calibration likely due to a shifting energy spectrum, (iii) a count-rate dependent layer identification, (iv) scatter fraction ranging from ∼ 42% to 54% where the variability was partly related to the shifting of the energy spectrum, (v) sensitivity ranging from ∼ 5.5% to 6.5% across centres, (vi) resolution of ∼ (2.5mm)3, fairly consistent across centres, (vii) image quality which is very comparable to other scanners.",

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AU - Camborde, Marie Laure

AU - Comtat, Claude

AU - Eriksson, Lars A.

AU - Houle, Sylvain

AU - Keator, David

AU - Knöß, Christof

AU - Krais, Roman

AU - Lammertsma, Adriaan A.

AU - Rahmim, Arman

AU - Sibomana, Mérence

AU - Teräs, Mika

AU - Thompson, Christopher J.

AU - Trébossen, Régine

AU - Votaw, John

AU - Walker, Matthew

AU - Wienhard, Klaus

AU - Wong, Dean F.

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AB - The high resolution research tomograph (HRRT) is one of the most complex existing Positron Emission Tomographs: it is the only human size scanner capable of decoding the depth of the γ-ray interaction in the crystal, using a lutetium LSO/LYSO phoswitch detector arrangement. In this study we determined basic scanner hardware characteristics, such as scanner data acquisition stability, and their variability across eleven centres. In addition a subset of the NEMA NU-2001 standards measurements was performed. We found (i) significant variability in the DOI decoding results between centres, (ii) a trend toward an increasing number of detected true coincident events as a function of elapsed time from scanner calibration likely due to a shifting energy spectrum, (iii) a count-rate dependent layer identification, (iv) scatter fraction ranging from ∼ 42% to 54% where the variability was partly related to the shifting of the energy spectrum, (v) sensitivity ranging from ∼ 5.5% to 6.5% across centres, (vi) resolution of ∼ (2.5mm)3, fairly consistent across centres, (vii) image quality which is very comparable to other scanners.

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ER -

The second generation HRRT - A multi-centre scanner performance investigation

Abstract

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Keywords

ASJC Scopus subject areas

Access to Document

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