The schizophrenia syndrome examples of biological tools for subclassification

Richard Jed Wyatt, Steven G. Potkin, Joel E. Kleinman, Daniel R. Weinberger, Daniel J. Luchins, Dilip V. Jeste

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Six biological variables-platelet monoamine oxidase activity, urine phenylethylamine concentration, brain norepinephrine concentration, abnormalities on computerized tomog-raphy, lateralization asymmetries, and the presence or absence of tardive dyskinesia-are used to discriminate possible biological groups of schizophrenic patients. All variables successfully subclassify patients, some into divisions consistent with phenomological, psy-chosocial, or biochemical descriptions or hypotheses of schizophrenia. None of the measures, however, has sufficiently stood the test of time to be of clinical utility.

Original languageEnglish (US)
Pages (from-to)1-2
Number of pages2
JournalJournal of Nervous and Mental Disease
Issue number2
StatePublished - Feb 1981
Externally publishedYes

ASJC Scopus subject areas

  • Psychiatry and Mental health


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