The role of duplex scanning versus angiography in predicting outcome after balloon angioplasty in the femoropopliteal artery

Mark W. Mewissen, Edward V. Kinney, Dennis F. Bandyk, Thomas Reifsnyder, Gary R. Seabrook, Elliot O. Lipchik, Jonathan B. Towne

Research output: Contribution to journalArticlepeer-review

66 Scopus citations


Duplex-derived velocity measurements were used to assess the hemodynamics of 64 femoropopliteal arterial sites in 59 patients after angiographically successful percutaneous transluminal balloon angioplasty. With use of angiography as the gold standard, percutaneous transluminal balloon angioplasty was judged to be successful if (1) evidence existed of a "split" caused by intimal dissection and splitting of atherosclerotic plaque; and (2) no significant diameter-reducing residual stenosis was observed at the percutaneous transluminal balloon angioplasty site. At 1 month, 55 limbs (86%) were hemodynamically and clinically improved by SVS/ISCVS clinical criteria for chronic limb ischemia. Of the 55 percutaneous transluminal balloon angioplasty sites, duplex scanning had identified 40 (63%) sites with a <50% diameter-reducing stenosis and 15 (27%) sites with a >50% diameter-reducing stenosis within a week after percutaneous transluminal balloon angioplasty. Independent review of the 55 angiograms taken after percutaneous transluminal balloon angioplasty identified 39 sites (71%) with a split and 16 sites (29%) without. By life-table analysis, a >50% diameter-reducing stenosis predicted a worse clinical outcome (15% at 1 year) compared with the presence of a <50% diameter-reducing stenosis (84% at 1 year) (p < 0.001; log rank test). The presence or absence of an angiographic split was not a predictive factor of percutaneous transluminal balloon angioplasty outcome (split, 61% at 1 year; no split, 62% at 1 year) (p = 0.832; log rank test). The detection of a functional residual stenosis by duplex scanning did not correlate with angiographic appearance, but was predictive of clinical failure. Normalization of flow hemodynamics in the treated arterial segment was associated with percutaneous transluminal balloon angioplasty durability.

Original languageEnglish (US)
Pages (from-to)860-865
Number of pages6
JournalJournal of vascular surgery
Issue number5
StatePublished - May 1992
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'The role of duplex scanning versus angiography in predicting outcome after balloon angioplasty in the femoropopliteal artery'. Together they form a unique fingerprint.

Cite this