The role of a midbrain network in competitive stimulus selection

Shreesh P. Mysore; Eric I. Knudsen

doi:10.1016/j.conb.2011.05.024

The role of a midbrain network in competitive stimulus selection

Research output: Contribution to journal › Review article › peer-review

Abstract

A midbrain network interacts with the well-known frontoparietal forebrain network to select stimuli for gaze and spatial attention. The midbrain network, containing the superior colliculus (SC; optic tectum, OT, in non-mammalian vertebrates) and the isthmic nuclei, helps evaluate the relative priorities of competing stimuli and encodes them in a topographic map of space. Behavioral experiments in monkeys demonstrate an essential contribution of the SC to stimulus selection when the relative priorities of competing stimuli are similar. Neurophysiological results from the owl OT demonstrate a neural correlate of this essential contribution of the SC/OT. The multi-layered, spatiotopic organization of the midbrain network lends itself to the analysis and modeling of the mechanisms underlying stimulus selection for gaze and spatial attention.

Original language	English (US)
Pages (from-to)	653-660
Number of pages	8
Journal	Current Opinion in Neurobiology
Volume	21
Issue number	4
DOIs	https://doi.org/10.1016/j.conb.2011.05.024
State	Published - Aug 2011
Externally published	Yes

ASJC Scopus subject areas

General Neuroscience

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10.1016/j.conb.2011.05.024

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@article{46d0a7882ff5476fb498d1ff4b94672f,

title = "The role of a midbrain network in competitive stimulus selection",

abstract = "A midbrain network interacts with the well-known frontoparietal forebrain network to select stimuli for gaze and spatial attention. The midbrain network, containing the superior colliculus (SC; optic tectum, OT, in non-mammalian vertebrates) and the isthmic nuclei, helps evaluate the relative priorities of competing stimuli and encodes them in a topographic map of space. Behavioral experiments in monkeys demonstrate an essential contribution of the SC to stimulus selection when the relative priorities of competing stimuli are similar. Neurophysiological results from the owl OT demonstrate a neural correlate of this essential contribution of the SC/OT. The multi-layered, spatiotopic organization of the midbrain network lends itself to the analysis and modeling of the mechanisms underlying stimulus selection for gaze and spatial attention.",

author = "Mysore, {Shreesh P.} and Knudsen, {Eric I.}",

note = "Funding Information: Funding from the Stanford University School of Medicine (Dean's Postdoctoral Fellowship, SPM) and the NIH (R01 EY019179 to EIK) is gratefully acknowledged. We thank Phyllis Knudsen for preparing the figures. We also thank Ali Asadollahi, Astra Bryant, Cathy Dunn, Yvette Fisher, Alex Goddard, and Jason Schwarz for critically reading the manuscript.",

year = "2011",

month = aug,

doi = "10.1016/j.conb.2011.05.024",

language = "English (US)",

volume = "21",

pages = "653--660",

journal = "Current Opinion in Neurobiology",

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AU - Mysore, Shreesh P.

AU - Knudsen, Eric I.

N1 - Funding Information: Funding from the Stanford University School of Medicine (Dean's Postdoctoral Fellowship, SPM) and the NIH (R01 EY019179 to EIK) is gratefully acknowledged. We thank Phyllis Knudsen for preparing the figures. We also thank Ali Asadollahi, Astra Bryant, Cathy Dunn, Yvette Fisher, Alex Goddard, and Jason Schwarz for critically reading the manuscript.

PY - 2011/8

Y1 - 2011/8

N2 - A midbrain network interacts with the well-known frontoparietal forebrain network to select stimuli for gaze and spatial attention. The midbrain network, containing the superior colliculus (SC; optic tectum, OT, in non-mammalian vertebrates) and the isthmic nuclei, helps evaluate the relative priorities of competing stimuli and encodes them in a topographic map of space. Behavioral experiments in monkeys demonstrate an essential contribution of the SC to stimulus selection when the relative priorities of competing stimuli are similar. Neurophysiological results from the owl OT demonstrate a neural correlate of this essential contribution of the SC/OT. The multi-layered, spatiotopic organization of the midbrain network lends itself to the analysis and modeling of the mechanisms underlying stimulus selection for gaze and spatial attention.

AB - A midbrain network interacts with the well-known frontoparietal forebrain network to select stimuli for gaze and spatial attention. The midbrain network, containing the superior colliculus (SC; optic tectum, OT, in non-mammalian vertebrates) and the isthmic nuclei, helps evaluate the relative priorities of competing stimuli and encodes them in a topographic map of space. Behavioral experiments in monkeys demonstrate an essential contribution of the SC to stimulus selection when the relative priorities of competing stimuli are similar. Neurophysiological results from the owl OT demonstrate a neural correlate of this essential contribution of the SC/OT. The multi-layered, spatiotopic organization of the midbrain network lends itself to the analysis and modeling of the mechanisms underlying stimulus selection for gaze and spatial attention.

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The role of a midbrain network in competitive stimulus selection

Abstract

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