The "psychomicrobiotic": Targeting microbiota in major psychiatric disorders: A systematic review

G. Fond; W. Boukouaci; G. Chevalier; A. Regnault; G. Eberl; N. Hamdani; F. Dickerson; A. Macgregor; L. Boyer; A. Dargel; J. Oliveira; R. Tamouza; M. Leboyer

doi:10.1016/j.patbio.2014.10.003

The "psychomicrobiotic": Targeting microbiota in major psychiatric disorders: A systematic review

G. Fond, W. Boukouaci, G. Chevalier, A. Regnault, G. Eberl, N. Hamdani, F. Dickerson, A. Macgregor, L. Boyer, A. Dargel, J. Oliveira, R. Tamouza, M. Leboyer

Research output: Contribution to journal › Article › peer-review

124 Scopus citations

Abstract

The gut microbiota is increasingly considered as a symbiotic partner in the maintenance of good health. Metagenomic approaches could help to discover how the complex gut microbial ecosystem participates in the control of the host's brain development and function, and could be relevant for future therapeutic developments, such as probiotics, prebiotics and nutritional approaches for psychiatric disorders. Previous reviews focused on the effects of microbiota on the central nervous system in in vitro and animal studies. The aim of the present review is to synthetize the current data on the association between microbiota dysbiosis and onset and/or maintenance of major psychiatric disorders, and to explore potential therapeutic opportunities targeting microbiota dysbiosis in psychiatric patients.

Original language	English (US)
Pages (from-to)	35-42
Number of pages	8
Journal	Pathologie Biologie
Volume	63
Issue number	1
DOIs	https://doi.org/10.1016/j.patbio.2014.10.003
State	Published - Feb 1 2015
Externally published	Yes

Keywords

Anxiety
Autism
Microbiota dysbiosis
Probiotic
Schizophrenia

ASJC Scopus subject areas

Pathology and Forensic Medicine

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10.1016/j.patbio.2014.10.003

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AU - Eberl, G.

AU - Hamdani, N.

AU - Dickerson, F.

AU - Macgregor, A.

AU - Boyer, L.

AU - Dargel, A.

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AU - Tamouza, R.

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The "psychomicrobiotic": Targeting microbiota in major psychiatric disorders: A systematic review

Abstract

Keywords

ASJC Scopus subject areas

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