The prevalence of bipolar disorders and association with quality of life in a cohort of patients with multiple sclerosis

Adalia H. Jun-O’connell; Ankur Butala; Idanis Berrios Morales; Nils Henninger; Kristina M. Deligiannidis; Nancy Byatt; Carolina Ionete

doi:10.1176/appi.neuropsych.15120403

The prevalence of bipolar disorders and association with quality of life in a cohort of patients with multiple sclerosis

Adalia H. Jun-O’connell, Ankur Butala, Idanis Berrios Morales, Nils Henninger, Kristina M. Deligiannidis, Nancy Byatt, Carolina Ionete

School of Medicine

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Clinical observations of mood instability in multiple sclerosis (MS) have led to the hypothesis that bipolar disorder (BD) may be more prevalent in persons with MS than in the general population. This cross-sectional study assesses the prevalence of BD among patients with MS using standardized psychiatric diagnostic interviews and evaluates quality of life. This study demonstrates a higher prevalence of BD in patients with MS compared with the general population. It also reveals the negative impact of BD on quality of life, raises the concern that BD can occur before the onset of neurological symptoms in MS, and suggests that, in some cases, BD may delay diagnosis of MS.

Original language	English (US)
Pages (from-to)	45-51
Number of pages	7
Journal	Journal of Neuropsychiatry and Clinical Neurosciences
Volume	29
Issue number	1
DOIs	https://doi.org/10.1176/appi.neuropsych.15120403
State	Published - 2017

ASJC Scopus subject areas

Clinical Neurology
Psychiatry and Mental health

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abstract = "Clinical observations of mood instability in multiple sclerosis (MS) have led to the hypothesis that bipolar disorder (BD) may be more prevalent in persons with MS than in the general population. This cross-sectional study assesses the prevalence of BD among patients with MS using standardized psychiatric diagnostic interviews and evaluates quality of life. This study demonstrates a higher prevalence of BD in patients with MS compared with the general population. It also reveals the negative impact of BD on quality of life, raises the concern that BD can occur before the onset of neurological symptoms in MS, and suggests that, in some cases, BD may delay diagnosis of MS.",

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AU - Deligiannidis, Kristina M.

AU - Byatt, Nancy

AU - Ionete, Carolina

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The prevalence of bipolar disorders and association with quality of life in a cohort of patients with multiple sclerosis

Abstract

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