TY - JOUR
T1 - The prescription opioid and heroin crisis
T2 - A public health approach to an epidemic of addiction
AU - Kolodny, Andrew
AU - Courtwright, David T.
AU - Hwang, Catherine S.
AU - Kreiner, Peter
AU - Eadie, John L.
AU - Clark, Thomas W.
AU - Alexander, G. Caleb
N1 - Publisher Copyright:
Copyright © 2015 by Annual Reviews. All rights reserved.
PY - 2015/3/18
Y1 - 2015/3/18
N2 - Public health authorities have described, with growing alarm, an unprecedented increase inmorbidity and mortality associated with use of opioid pain relievers (OPRs). Efforts to address the opioid crisis have focused mainly on reducing nonmedical OPR use. Too often overlooked, however, is the need for preventing and treating opioid addiction, which occurs in both medical and nonmedical OPR users. Overprescribing of OPRs has led to a sharp increase in the prevalence of opioid addiction, which in turn has been associated with a rise in overdose deaths and heroin use. A multifaceted public health approach that utilizes primary, secondary, and tertiary opioid addiction prevention strategies is required to effectively reduce opioid-related morbidity and mortality. We describe the scope of this public health crisis, its historical context, contributing factors, and lines of evidence indicating the role of addiction in exacerbating morbidity and mortality, andwe provide a framework for interventions to address the epidemic of opioid addiction.
AB - Public health authorities have described, with growing alarm, an unprecedented increase inmorbidity and mortality associated with use of opioid pain relievers (OPRs). Efforts to address the opioid crisis have focused mainly on reducing nonmedical OPR use. Too often overlooked, however, is the need for preventing and treating opioid addiction, which occurs in both medical and nonmedical OPR users. Overprescribing of OPRs has led to a sharp increase in the prevalence of opioid addiction, which in turn has been associated with a rise in overdose deaths and heroin use. A multifaceted public health approach that utilizes primary, secondary, and tertiary opioid addiction prevention strategies is required to effectively reduce opioid-related morbidity and mortality. We describe the scope of this public health crisis, its historical context, contributing factors, and lines of evidence indicating the role of addiction in exacerbating morbidity and mortality, andwe provide a framework for interventions to address the epidemic of opioid addiction.
KW - Addiction
KW - Chronic pain
KW - Heroin
KW - Opioid
KW - Overdose deaths
KW - Prescription drug abuse
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UR - http://www.scopus.com/inward/citedby.url?scp=84925260632&partnerID=8YFLogxK
U2 - 10.1146/annurev-publhealth-031914-122957
DO - 10.1146/annurev-publhealth-031914-122957
M3 - Review article
C2 - 25581144
AN - SCOPUS:84925260632
SN - 0163-7525
VL - 36
SP - 559
EP - 574
JO - Annual Review of Public Health
JF - Annual Review of Public Health
ER -