The postoperative management of pain from intracranial surgery in pediatric neurosurgical patients

Joanne E. Shay, Deepa Kattail, Athir Morad, Myron Yaster

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


Pain following intracranial surgery has historically been undertreated because of the concern that opioids, the analgesics most commonly used to treat moderate-to-severe pain, will interfere with the neurologic examination and adversely affect postoperative outcome. Over the past decade, accumulating evidence, primarily in adult patients, has revealed that moderate-to-severe pain is common in neurosurgical patients following surgery. Using the neurophysiology of pain as a blueprint, we have highlighted some of the drugs and drug families used in multimodal pain management. This analgesic method minimizes opioid-induced adverse side effects by maximizing pain control with smaller doses of opioids supplemented with neural blockade and nonopioid analgesics, such nonsteroidal antiinflammatory drugs, local anesthetics, corticosteroids, N-methyl-D-aspartate (NMDA) antagonists, α2- adrenergic agonists, and/or anticonvulsants (gabapentin and pregabalin).

Original languageEnglish (US)
Pages (from-to)724-733
Number of pages10
JournalPaediatric anaesthesia
Issue number7
StatePublished - Jul 2014


  • age
  • analgesics
  • nervous system physiology
  • neurosurgery
  • pain management
  • patient-controlled analgesia
  • pediatric

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Anesthesiology and Pain Medicine


Dive into the research topics of 'The postoperative management of pain from intracranial surgery in pediatric neurosurgical patients'. Together they form a unique fingerprint.

Cite this