The polka dot liver and spleen: a case report.

D. H. Van Thiel, T. Hassanein, A. Gurakar, P. Caraceni, A. Nadir, H. I. Wright

Research output: Contribution to journalArticlepeer-review


Hepatomegaly occurring in association with an inhomogeneous liver documented on CT scanning in an individual with abnormal liver injury parameters is a common clinical finding. In most such cases, an increase in the canalicular enzymes (alkaline phosphatase and gamma-glutamyl transpeptidase) is present. Most individuals with this combination of findings are ill-appearing individuals with metastatic cancer. The same findings in an individual with few symptoms or one who appears quite fit is unusual and presents a unique problem in differential diagnosis. Herein we present such a case that, with appropriate medical therapy, had a near complete resolution of the biochemical and radiologic manifestations of disease.

Original languageEnglish (US)
Pages (from-to)7-10
Number of pages4
JournalThe Journal of the Oklahoma State Medical Association
Issue number1
StatePublished - Jan 1995
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine


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