TY - JOUR
T1 - The Ophthalmic Manifestations of Down Syndrome
AU - Sun, Emily
AU - Kraus, Courtney L.
N1 - Publisher Copyright:
© 2023 by the authors.
PY - 2023/2
Y1 - 2023/2
N2 - Down Syndrome is one of the most common chromosomal conditions in the world, affecting an estimated 1:400–1:500 births. It is a multisystem genetic disorder but has a wide range of ophthalmic findings. These include strabismus, amblyopia, accommodation defects, refractive error, eyelid abnormalities, nasolacrimal duct obstruction, nystagmus, keratoconus, cataracts, retinal abnormalities, optic nerve abnormalities, and glaucoma. These ophthalmic conditions are more prevalent in children with Down Syndrome than the general pediatric population, and without exception, early identification with thoughtful screening in this patient population can drastically improve prognosis and/or quality of life.
AB - Down Syndrome is one of the most common chromosomal conditions in the world, affecting an estimated 1:400–1:500 births. It is a multisystem genetic disorder but has a wide range of ophthalmic findings. These include strabismus, amblyopia, accommodation defects, refractive error, eyelid abnormalities, nasolacrimal duct obstruction, nystagmus, keratoconus, cataracts, retinal abnormalities, optic nerve abnormalities, and glaucoma. These ophthalmic conditions are more prevalent in children with Down Syndrome than the general pediatric population, and without exception, early identification with thoughtful screening in this patient population can drastically improve prognosis and/or quality of life.
KW - Down Syndrome
KW - Trisomy 21
KW - amblyopia
KW - nasolacrimal duct obstruction
KW - strabismus
UR - http://www.scopus.com/inward/record.url?scp=85148591847&partnerID=8YFLogxK
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U2 - 10.3390/children10020341
DO - 10.3390/children10020341
M3 - Review article
C2 - 36832470
AN - SCOPUS:85148591847
SN - 2227-9067
VL - 10
JO - Children
JF - Children
IS - 2
M1 - 341
ER -