@article{3d2cce7292f24ad29b41ac875e06e8ad,
title = "The mutation significance cutoff: gene-level thresholds for variant predictions",
author = "Yuval Itan and Lei Shang and Bertrand Boisson and Ciancanelli, \{Michael J.\} and Markle, \{Janet G.\} and Ruben Martinez-Barricarte and Eric Scott and Ishaan Shah and Stenson, \{Peter D.\} and Joseph Gleeson and Cooper, \{David N.\} and Lluis Quintana-Murci and Zhang, \{Shen Ying\} and Laurent Abel and Casanova, \{Jean Laurent\}",
note = "Funding Information: We thank M. Kircher for information about the CADD method and D.B. Goldstein for gene-level metrics insights. We thank Y. Nemirovskaya, E. Anderson, M. Woollett and D. Papandrea for administrative support. Y.I. was supported in part by grant no. UL1 TR000043 from the National Center for Advancing Translational Sciences (NCATS), US National Institutes of Health (NIH) Clinical and Translational Science Award (CTSA) program. This study was supported by the Rockefeller University and the St. Giles Foundation.",
year = "2016",
month = feb,
day = "1",
doi = "10.1038/nmeth.3739",
language = "English (US)",
volume = "13",
pages = "109--110",
journal = "Nature Methods",
issn = "1548-7091",
number = "2",
}