Abstract
1. The metabolism of azidomorphine, a potent narcotic analgesic, was studied in a human subject who had received a single 1·8 mg dose subcutaneously. 2. Azidomorphine was excreted in the urine in small amounts as the intact drug and as a metabolite, 6-deoxy-6 aminodihydromorphine. Larger amounts of conjugated azidomorphine also were detected. 3. The azido group of azidomorphine was relatively stable towards enzymic and chemical change.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 301-304 |
| Number of pages | 4 |
| Journal | Xenobiotica |
| Volume | 8 |
| Issue number | 5 |
| DOIs | |
| State | Published - 1978 |
| Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Toxicology
- Pharmacology
- Health, Toxicology and Mutagenesis