TY - JOUR
T1 - The maternal and newborn health registry study of the global network for women's and children's health research
AU - Goudar, Shivaprasad S.
AU - Carlo, Waldemar A.
AU - McClure, Elizabeth M.
AU - Pasha, Omrana
AU - Patel, Archana
AU - Esamai, Fabian
AU - Chomba, Elwyn
AU - Garces, Ana
AU - Althabe, Fernando
AU - Kodkany, Bhalachandra
AU - Sami, Neelofar
AU - Derman, Richard J.
AU - Hibberd, Patricia L.
AU - Liechty, Edward A.
AU - Krebs, Nancy F.
AU - Hambidge, K. Michael
AU - Buekens, Pierre
AU - Moore, Janet
AU - Wallace, Dennis
AU - Jobe, Alan H.
AU - Koso-Thomas, Marion
AU - Wright, Linda L.
AU - Goldenberg, Robert L.
N1 - Funding Information:
The present study was conducted under the auspices of the Global Network, which is a multi-country research network funded by the NICHD. Investigators from each site, the NICHD, and the Data Coordination Center (DCC) constitute the Maternal Newborn Health (MNH) Registry Study Committee, which oversees protocol design, study implementation, data analyses, and publications. Within each Global Network site, the registry is overseen by the senior investigator, the study coordinator, and his/her designee, who ensure overall completeness and data quality. Study sites in each country (Argentina, Guatemala, India [2 sites], Kenya, Pakistan, and Zambia) have established research infrastructure in 6–24 distinct geographic areas (clusters), appropriate for long-term registry data collection and ongoing Global Network research. Each cluster was selected with a target birth rate of 300–500 deliveries per year. Specifically, the clusters were generally formed based on the existing healthcare service delivery areas, as defined by the Ministry of Health in the participating countries. For example, the Primary Health Centers (PHCs) were the basis of the clusters in India. The PHCs typically serve a defined population and the births were estimated via the birth rates from the available Ministry of Health data. To oversee data collection, each study cluster employs designated Registry Administrators (RAs), who are well-respected healthcare providers within the community. The RAs—who work closely with the existing healthcare service providers within their communities and, in turn, enhance the healthcare delivery system—receive ongoing central training, including data form completion, data monitoring and editing, and quality improvement. The RAs monitor the pregnancies in the cluster, facilitated by local informants (e.g. village elders, birth attendants, and facility registries).
PY - 2012/9
Y1 - 2012/9
N2 - Objective: To implement a vital statistics registry system to register pregnant women and document birth outcomes in the Global Network for Women's and Children's Health Research sites in Asia, Africa, and Latin America. Methods: The Global Network sites began a prospective population-based pregnancy registry to identify all pregnant women and record pregnancy outcomes up to 42 days post-delivery in more than 100 defined low-resource geographic areas (clusters). Pregnant women were registered during pregnancy, with 42-day maternal and neonatal follow-up recorded - including care received during the pregnancy and postpartum periods. Recorded outcomes included stillbirth, neonatal mortality, and maternal mortality rates. Results: In 2010, 72 848 pregnant women were enrolled and 6-week follow-up was obtained for 97.8%. Across sites, 40.7%, 24.8%, and 34.5% of births occurred in a hospital, health center, and home setting, respectively. The mean neonatal mortality rate was 23 per 1000 live births, ranging from 8.2 to 48.5 per 1000 live births. The mean stillbirth rate ranged from 13.7 to 54.4 per 1000 births. Conclusion: The registry is an ongoing study to assess the impact of interventions and trends regarding pregnancy outcomes and measures of care to inform public health. ClinicalTrial.gov Trial Registration: NCT01073475
AB - Objective: To implement a vital statistics registry system to register pregnant women and document birth outcomes in the Global Network for Women's and Children's Health Research sites in Asia, Africa, and Latin America. Methods: The Global Network sites began a prospective population-based pregnancy registry to identify all pregnant women and record pregnancy outcomes up to 42 days post-delivery in more than 100 defined low-resource geographic areas (clusters). Pregnant women were registered during pregnancy, with 42-day maternal and neonatal follow-up recorded - including care received during the pregnancy and postpartum periods. Recorded outcomes included stillbirth, neonatal mortality, and maternal mortality rates. Results: In 2010, 72 848 pregnant women were enrolled and 6-week follow-up was obtained for 97.8%. Across sites, 40.7%, 24.8%, and 34.5% of births occurred in a hospital, health center, and home setting, respectively. The mean neonatal mortality rate was 23 per 1000 live births, ranging from 8.2 to 48.5 per 1000 live births. The mean stillbirth rate ranged from 13.7 to 54.4 per 1000 births. Conclusion: The registry is an ongoing study to assess the impact of interventions and trends regarding pregnancy outcomes and measures of care to inform public health. ClinicalTrial.gov Trial Registration: NCT01073475
KW - Maternal mortality
KW - Neonatal mortality
KW - Perinatal mortality
KW - Pregnancy
KW - Registry
KW - Stillbirth
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U2 - 10.1016/j.ijgo.2012.04.022
DO - 10.1016/j.ijgo.2012.04.022
M3 - Article
C2 - 22738806
AN - SCOPUS:84864580898
SN - 0020-7292
VL - 118
SP - 190
EP - 193
JO - International Journal of Gynecology and Obstetrics
JF - International Journal of Gynecology and Obstetrics
IS - 3
ER -