The Major Physiological Control Mechanisms of Blood Flow and Oxygen Delivery

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish (US)
Title of host publicationChemistry and Biochemistry of Oxygen Therapeutics
Subtitle of host publicationFrom Transfusion to Artificial Blood
PublisherJohn Wiley and Sons
Number of pages23
ISBN (Print)9780470686683
StatePublished - Jul 4 2011


  • Blood flow autoregulation - and perfusion pressure changes
  • Blood flow autoregulation - fundamental characteristic of vasoregulation
  • Blood flow metabolic regulation - in tissues
  • Bulk O2 transport to microcirculation - product of arterial O2 content, and blood flow
  • Carbon monoxide hypoxia - decrease in CaO2 and decrease in p50
  • Major physiological control mechanisms - of blood flow and oxygen delivery
  • Perfusion of microcirculation - and arterio-venous pressure gradient
  • Primary mechanism of myogenic response - stretch-activated channel stimulation
  • Vascular smooth muscle - and intrinsic myogenic tone, with transmural pressure
  • Vasomotor tone, endothelial control - in vascular smooth muscle regulation

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology

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