The ketogenic diet in pharmacoresistant childhood epilepsy

Steven Parrish Winesett, Stacey Kordecki Bessone, Eric H.W. Kossoff

Research output: Contribution to journalReview articlepeer-review

39 Scopus citations


Available pharmacologic treatments for seizures are limited in their efficacy. For a patient with seizures, pharmacologic treatment with available anticonvulsant medications leads to seizure control in <70% of patients. Surgical resection can lead to control in a select subset of patients but still leaves a significant number of patients with uncontrolled seizures. The ketogenic diet and related diets have proven to be useful in pharmacoresistant childhood epilepsy.

Original languageEnglish (US)
Pages (from-to)621-628
Number of pages8
JournalExpert review of neurotherapeutics
Issue number6
StatePublished - Jun 1 2015


  • GLUT-1 deficiency
  • MCT diet
  • doose syndrome
  • epilepsy
  • infantile spasms
  • ketogenic
  • lennox-gastaut syndrome
  • low glycemic index diet
  • modified atkins diet
  • seizures

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology
  • Pharmacology (medical)


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