Abstract
The ketogenic diet is one of the oldest therapies for epilepsy. Now, as in the 1920's 15-30% of children with medicationrefractory seizures will have their seizures controlled with this carefully calculated, high fat-low protein-virtually no CHO diet. An additional 30-40% of children will have a greater than 50% reduction of seizures. For approximately 30% the diet is not sufficiently effective to continue. While eclipsed by anticonvulsants for several decades, the diet's recent resurgence for medication-refractory seizures in children has reawakened interest in its possible mechanisms of action. Recent studies of efficacy and directions for future research will be discussed.
Original language | English (US) |
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Pages (from-to) | A735 |
Journal | FASEB Journal |
Volume | 10 |
Issue number | 3 |
State | Published - Dec 1 1996 |
ASJC Scopus subject areas
- Biotechnology
- Biochemistry
- Molecular Biology
- Genetics