@inbook{ef1138122d094d4aabf94f4c41af0e35,
title = "The intricate metabolism of pancreatic cancers",
abstract = "Oncogenic KRAS regulates glucose and glutamine metabolism in pancreatic cancer cells.MUC1 overexpression leads to increased glucose metabolism.p53 functions predict the sensitivity of pancreatic cancer tumors to glycolytic inhibition.Targeting alpha-ketoglutarate dehydrogenase function by CPI-613 to slow mitochondrial metabolism.The antidiabetic drug, metformin, targets pancreatic cancer stem cells.Combined therapy is used to target pancreatic metabolism heterogeneity.",
keywords = "Combined therapy, Glucose metabolism, Glutamine metabolism, KRAS mutation, Pancreatic ductal adenocarcinoma",
author = "Felipe Camelo and Anne Le",
note = "Publisher Copyright: {\textcopyright} 2018, Springer International Publishing AG, part of Springer Nature.",
year = "2018",
doi = "10.1007/978-3-319-77736-8_5",
language = "English (US)",
series = "Advances in Experimental Medicine and Biology",
publisher = "Springer New York LLC",
pages = "73--81",
booktitle = "Advances in Experimental Medicine and Biology",
}