The incredible shrinking world of DNA microarrays

Sarah J. Wheelan, Francisco Martínez Murillo, Jef D. Boeke

Research output: Contribution to journalReview articlepeer-review

25 Scopus citations

Abstract

The efficacy of microarrays in examining gene expression, gene and genome structure, protein-DNA interactions, whole-genome similarities and differences, microRNA expression, methylation (and more) is no longer in question. It is a fast-developing, cutting edge technology that has grown up along with massive sequence databases and is likely to become part of everyday patient care. Many advances have recently expanded the power and utility of microarrays; among them is our development of a new array tiling technique that dramatically increases the scope of coverage of an oligonucleotide tiling array without substantially increasing its cost.

Original languageEnglish (US)
Pages (from-to)726-732
Number of pages7
JournalMolecular BioSystems
Volume4
Issue number7
DOIs
StatePublished - 2008

ASJC Scopus subject areas

  • Biotechnology
  • Molecular Biology

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