TY - JOUR
T1 - The Incidence and Outcomes of Surgical Pulmonary Embolectomy in North America
AU - Kon, Zachary N.
AU - Pasrija, Chetan
AU - Bittle, Gregory J.
AU - Vemulapalli, Sreekanth
AU - Grau-Sepulveda, Maria V.
AU - Matsouaka, Roland
AU - Deatrick, Kristopher B.
AU - Taylor, Bradley S.
AU - Gammie, James S.
AU - Griffith, Bartley P.
N1 - Publisher Copyright:
© 2019 The Society of Thoracic Surgeons
PY - 2019/5
Y1 - 2019/5
N2 - Background: There has been renewed interest in surgical pulmonary embolectomy (SPE) for the treatment of pulmonary embolism, but the real-world incidence and outcomes of SPE have yet to be well described using a large, granular data set. We examined the modern experience with SPE in North America as reported to the Society of Thoracic Surgery Adult Cardiac Surgery Database (STS ACSD). Methods: The STS ACSD was queried for all isolated SPE for the treatment of acute pulmonary embolism (2011 to 2015). Groups were stratified based on presentation: no cardiogenic shock (NCS), cardiogenic shock without arrest (CS), and cardiogenic shock with cardiac arrest (CS/CA). Preoperative characteristics, intraoperative variables, postoperative in-hospital complications, and operative mortality were compared. Multivariable logistic regression was performed to identify risk factors for in-hospital mortality. Results: Of the 1,144 centers reporting during the study period, only 310 performed at least 1 SPE (overall mean, 0.42 ± 1.03 cases • year -1 • center -1 ). A total of 1,075 eligible SPE were identified (NCS = 719, CS = 203, CS/CA = 153). Median age was 57 years (interquartile range, 45 to 67), 54% were male, and preoperative thrombolysis was used in 8%. Overall, operative mortality was 16%, but increased with presenting acuity (NCS = 8%, CS = 23%, CS/CA = 44%, p < 0.001). Independent predictors of operative mortality included age, obesity, cardiogenic shock, preoperative arrest, chronic lung disease, unresponsive neurologic state, and prolonged cardiopulmonary bypass time. Conclusions: SPE is uncommonly performed in North America, and, in selected patients, it may be associated with favorable outcomes. Nevertheless, significant mortality exists, and attention to patient presentation and other risk factors may help distinguish patients appropriate for SPE.
AB - Background: There has been renewed interest in surgical pulmonary embolectomy (SPE) for the treatment of pulmonary embolism, but the real-world incidence and outcomes of SPE have yet to be well described using a large, granular data set. We examined the modern experience with SPE in North America as reported to the Society of Thoracic Surgery Adult Cardiac Surgery Database (STS ACSD). Methods: The STS ACSD was queried for all isolated SPE for the treatment of acute pulmonary embolism (2011 to 2015). Groups were stratified based on presentation: no cardiogenic shock (NCS), cardiogenic shock without arrest (CS), and cardiogenic shock with cardiac arrest (CS/CA). Preoperative characteristics, intraoperative variables, postoperative in-hospital complications, and operative mortality were compared. Multivariable logistic regression was performed to identify risk factors for in-hospital mortality. Results: Of the 1,144 centers reporting during the study period, only 310 performed at least 1 SPE (overall mean, 0.42 ± 1.03 cases • year -1 • center -1 ). A total of 1,075 eligible SPE were identified (NCS = 719, CS = 203, CS/CA = 153). Median age was 57 years (interquartile range, 45 to 67), 54% were male, and preoperative thrombolysis was used in 8%. Overall, operative mortality was 16%, but increased with presenting acuity (NCS = 8%, CS = 23%, CS/CA = 44%, p < 0.001). Independent predictors of operative mortality included age, obesity, cardiogenic shock, preoperative arrest, chronic lung disease, unresponsive neurologic state, and prolonged cardiopulmonary bypass time. Conclusions: SPE is uncommonly performed in North America, and, in selected patients, it may be associated with favorable outcomes. Nevertheless, significant mortality exists, and attention to patient presentation and other risk factors may help distinguish patients appropriate for SPE.
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U2 - 10.1016/j.athoracsur.2018.10.035
DO - 10.1016/j.athoracsur.2018.10.035
M3 - Article
C2 - 30476479
AN - SCOPUS:85063086058
SN - 0003-4975
VL - 107
SP - 1401
EP - 1408
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
IS - 5
ER -