The impact of sildenafil on molecular science and sexual health

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


Objective: Sexual medicine has evolved greatly in the past several years, to a large extent because of the introduction of the phosphodiesterase-5 (PDE5) inhibitor, Viagra (sildenafil citrate), as a highly effective oral therapy for erectile dysfunction. Methods: Recent literature pertaining to the development and clinical applications of sildenafil citrate was reviewed. Results: The emergence of PDE5 inhibitor therapy for erectile dysfunction represents a major scientific and clinical breakthrough, and it has impacted on the field in such prominent areas as scientific discovery, clinical management, and public health awareness of sexual health disorders. Conclusion: The development of sildenafil citrate has had a major role in advancing the field of sexual medicine.

Original languageEnglish (US)
Pages (from-to)9-14
Number of pages6
JournalEuropean Urology
Issue number1
StatePublished - Jul 1 2004


  • Penile erection
  • Sexual function
  • Sildenafil
  • Viagra

ASJC Scopus subject areas

  • Urology


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