The Impact and Management of Fibroids for Fertility. An Evidence-Based Approach

Xiaoxiao Catherine Guo, James H. Segars

Research output: Contribution to journalReview articlepeer-review

50 Scopus citations


Fibroids affect 35% to 77% of reproductive-age women. When selecting a treatment plan for symptomatic fibroids, the fibroid location, size, and number must be considered. Myomectomy remains the preferred method for women with fibroid-related infertility who wish to have children or maintain fertility. Currently available medical therapies reduce symptoms in the short term but may involve side effects when used long term. Initial fertility studies are encouraging but trials are needed. Recent medical advances have led to minimally invasive approaches for women with fibroid disease, but there is a strong demand for additional treatment options.

Original languageEnglish (US)
Pages (from-to)521-533
Number of pages13
JournalObstetrics and Gynecology Clinics of North America
Issue number4
StatePublished - Dec 2012
Externally publishedYes


  • Assisted reproductive technology (ART)
  • Hysteroscopy
  • Infertility
  • Leiomyoma
  • Magnetic resonance-guided focused ultrasound (MRgFUS)
  • Minimally invasive gynecologic surgeries
  • Myomectomy
  • Uterine artery embolization (UAE)

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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