The genetic control of liver cAMP levels in mice

William Lafuse, Daniel Meruelo, Michael Edidin

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Steady-state level of liver 3′,5′-cyclic monophosphate, cAMP, has been shown to be under genetic control linked to the mouse H-2 complex. Liver cAMP levels are associated with H-2 haplotype in fully segregating crosses of strains C3H and C57BL/10. In crosses involving strain A, other loci have an effect that swamps that of H-2. Results with H-2 recombinants indicate that liver cAMP levels are affected by more than one H-2-linked locus.

Original languageEnglish (US)
Pages (from-to)57-65
Number of pages9
Issue number1
StatePublished - Dec 1 1979

ASJC Scopus subject areas

  • Immunology
  • Genetics


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