TY - JOUR
T1 - The future of HIV Organ Policy Equity Act is now
T2 - The state of HIV+ to HIV+ kidney transplantation in the United States
AU - Boyarsky, Brian J.
AU - Bowring, Mary Grace
AU - Shaffer, Ashton A.
AU - Segev, Dorry L.
AU - Durand, Christine M.
N1 - Funding Information:
This work was supported by the National Institutes of Health grants K23CA177321-01A1 (C.M.D.), R34AI123023 (C.M.D.), U01AI134591 (C.M.D., D.L.S.), K24DK101828 (D.L.S.), F30DK11665 (A.A.S.), and Johns Hopkins University Center for AIDS Research 1P30AI094189 (C.M.D.).
Publisher Copyright:
© 2019 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2019/8/1
Y1 - 2019/8/1
N2 - Purpose of reviewWe report the current state of HIV+ to HIV+ kidney transplantation in the United States and remaining challenges in implementing this practice nationally.Recent findingsThe HIV Organ Policy Equity (HOPE) Act, which was the first step in unlocking the potential of HIV+ organ donors, mandates clinical research on HIV+ to HIV+ transplantation. As of March 2019, there have been 57 HOPE donors, including both true and false positive HOPE donors resulting in more than 120 transplants.SummaryThe HOPE Act, signed in 2013, reversed the federal ban on the transplantation of organs from HIV+ donors into HIV+ recipients. Ongoing national studies are exploring the safety, feasibility, and efficacy of both kidney and liver transplantation in this population. If successfully and fully implemented, HIV+ to HIV+ transplantation could attenuate the organ shortage for everyone waiting, resulting in a far-reaching public health impact.
AB - Purpose of reviewWe report the current state of HIV+ to HIV+ kidney transplantation in the United States and remaining challenges in implementing this practice nationally.Recent findingsThe HIV Organ Policy Equity (HOPE) Act, which was the first step in unlocking the potential of HIV+ organ donors, mandates clinical research on HIV+ to HIV+ transplantation. As of March 2019, there have been 57 HOPE donors, including both true and false positive HOPE donors resulting in more than 120 transplants.SummaryThe HOPE Act, signed in 2013, reversed the federal ban on the transplantation of organs from HIV+ donors into HIV+ recipients. Ongoing national studies are exploring the safety, feasibility, and efficacy of both kidney and liver transplantation in this population. If successfully and fully implemented, HIV+ to HIV+ transplantation could attenuate the organ shortage for everyone waiting, resulting in a far-reaching public health impact.
KW - HIV Organ Policy Equity Act
KW - HIV infection
KW - end-stage renal disease
KW - kidney transplant
KW - solid organ transplantation
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UR - http://www.scopus.com/inward/citedby.url?scp=85069329282&partnerID=8YFLogxK
U2 - 10.1097/MOT.0000000000000653
DO - 10.1097/MOT.0000000000000653
M3 - Review article
C2 - 31145154
AN - SCOPUS:85069329282
SN - 1087-2418
VL - 24
SP - 434
EP - 440
JO - Current Opinion in Organ Transplantation
JF - Current Opinion in Organ Transplantation
IS - 4
ER -