The effects of varying sodium concentrations on the metabolism of glutamine by the renal cortex of the rat

Janet Hawthorn; Jennifer A. Alexander; George A O Alleyne

doi:10.1159/000172655

The effects of varying sodium concentrations on the metabolism of glutamine by the renal cortex of the rat

Janet Hawthorn, Jennifer A. Alexander, George A O Alleyne

Research output: Contribution to journal › Article › peer-review

Abstract

We studied the effect of varying the sodium concentration on the tissue swelling and metabolism of renal cortical slices from control and acidotic rats. Lowering the sodium concentration in the incubation medium caused increased tissue swelling and depressed glutamine uptake, ammoniagenesis and gluconeogenesis in slices from both control and acidotic rats.

Original language	English (US)
Pages (from-to)	140-146
Number of pages	7
Journal	Kidney and Blood Pressure Research
Volume	1
Issue number	3
DOIs	https://doi.org/10.1159/000172655
State	Published - 1978
Externally published	Yes

Keywords

Acidosis
Ammonia
Glucose
Glutamine
Sodium

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Nephrology

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10.1159/000172655

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abstract = "We studied the effect of varying the sodium concentration on the tissue swelling and metabolism of renal cortical slices from control and acidotic rats. Lowering the sodium concentration in the incubation medium caused increased tissue swelling and depressed glutamine uptake, ammoniagenesis and gluconeogenesis in slices from both control and acidotic rats.",

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AU - Alleyne, George A O

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AB - We studied the effect of varying the sodium concentration on the tissue swelling and metabolism of renal cortical slices from control and acidotic rats. Lowering the sodium concentration in the incubation medium caused increased tissue swelling and depressed glutamine uptake, ammoniagenesis and gluconeogenesis in slices from both control and acidotic rats.

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KW - Ammonia

KW - Glucose

KW - Glutamine

KW - Sodium

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The effects of varying sodium concentrations on the metabolism of glutamine by the renal cortex of the rat

Abstract

Keywords

ASJC Scopus subject areas

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