Abstract
Clozapine has proved effective in alleviating a wide range of psychiatric symptoms in schizophrenia. Its effects on cognitive function in schizophrenia are more variable. Clozapine appears to have a salutary effect on some aspects of attention, response speed, and fluency, whereas it appears to have a mild but adverse effect on visual memory and some executive functions. This profile may be related to the affinity of clozapine for dopaminergic type I and muscarinic receptors and relative lack of affinity for dopaminergic type II receptors.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 88-90 |
| Number of pages | 3 |
| Journal | Journal of Clinical Psychiatry |
| Volume | 55 |
| Issue number | 9 SUPPL. B |
| State | Published - Nov 16 1994 |
| Externally published | Yes |
ASJC Scopus subject areas
- Psychiatry and Mental health