The effect of treatment with nitrendipine and other calcium channel blockers on the physiologic and pathologic changes caused by hypoxia in rats

John R. Michael; Thomas P. Kennedy; Philip Buescher; Imad Farrukh; Peter C. Rock; Gail Gurtner; Suzanne M. de la Monte; Grover M. Hutchins

doi:10.1097/00005344-198700094-00010

The effect of treatment with nitrendipine and other calcium channel blockers on the physiologic and pathologic changes caused by hypoxia in rats

John R. Michael, Thomas P. Kennedy, Philip Buescher, Imad Farrukh, Peter C. Rock, Gail Gurtner, Suzanne M. de la Monte, Grover M. Hutchins

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Nitrendipine and other calcium channel blokers acutely inhibit hypoxic pulmonary vasoconstriction and show promise in the prevention of the pulmonary vascular and cardiac changes produced by chronic alveolar hypoxia. This paper reviews the current information available from animal and clinical studies.

Original language	English (US)
Pages (from-to)	S61-S65
Journal	Journal of cardiovascular pharmacology
Volume	9
DOIs	https://doi.org/10.1097/00005344-198700094-00010
State	Published - Jan 1 1987

Keywords

Alveolar hypoxia
Nitrendipine
Pulmonary and cardiac changes

ASJC Scopus subject areas

Pharmacology
Cardiology and Cardiovascular Medicine

Access to Document

10.1097/00005344-198700094-00010

Cite this

Michael, J. R., Kennedy, T. P., Buescher, P., Farrukh, I., Rock, P. C., Gurtner, G., de la Monte, S. M., & Hutchins, G. M. (1987). The effect of treatment with nitrendipine and other calcium channel blockers on the physiologic and pathologic changes caused by hypoxia in rats. Journal of cardiovascular pharmacology, 9, S61-S65. https://doi.org/10.1097/00005344-198700094-00010

@article{b21384790e3d4888bd41ebfe24b17b55,

title = "The effect of treatment with nitrendipine and other calcium channel blockers on the physiologic and pathologic changes caused by hypoxia in rats",

abstract = "Nitrendipine and other calcium channel blokers acutely inhibit hypoxic pulmonary vasoconstriction and show promise in the prevention of the pulmonary vascular and cardiac changes produced by chronic alveolar hypoxia. This paper reviews the current information available from animal and clinical studies.",

keywords = "Alveolar hypoxia, Nitrendipine, Pulmonary and cardiac changes",

author = "Michael, {John R.} and Kennedy, {Thomas P.} and Philip Buescher and Imad Farrukh and Rock, {Peter C.} and Gail Gurtner and {de la Monte}, {Suzanne M.} and Hutchins, {Grover M.}",

year = "1987",

month = jan,

day = "1",

doi = "10.1097/00005344-198700094-00010",

language = "English (US)",

volume = "9",

pages = "S61--S65",

journal = "Journal of cardiovascular pharmacology",

issn = "0160-2446",

publisher = "Lippincott Williams and Wilkins",

}

TY - JOUR

T1 - The effect of treatment with nitrendipine and other calcium channel blockers on the physiologic and pathologic changes caused by hypoxia in rats

AU - Michael, John R.

AU - Kennedy, Thomas P.

AU - Buescher, Philip

AU - Farrukh, Imad

AU - Rock, Peter C.

AU - Gurtner, Gail

AU - de la Monte, Suzanne M.

AU - Hutchins, Grover M.

PY - 1987/1/1

Y1 - 1987/1/1

N2 - Nitrendipine and other calcium channel blokers acutely inhibit hypoxic pulmonary vasoconstriction and show promise in the prevention of the pulmonary vascular and cardiac changes produced by chronic alveolar hypoxia. This paper reviews the current information available from animal and clinical studies.

AB - Nitrendipine and other calcium channel blokers acutely inhibit hypoxic pulmonary vasoconstriction and show promise in the prevention of the pulmonary vascular and cardiac changes produced by chronic alveolar hypoxia. This paper reviews the current information available from animal and clinical studies.

KW - Alveolar hypoxia

KW - Nitrendipine

KW - Pulmonary and cardiac changes

UR - http://www.scopus.com/inward/record.url?scp=84930876073&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84930876073&partnerID=8YFLogxK

U2 - 10.1097/00005344-198700094-00010

DO - 10.1097/00005344-198700094-00010

M3 - Article

AN - SCOPUS:84930876073

SN - 0160-2446

VL - 9

SP - S61-S65

JO - Journal of cardiovascular pharmacology

JF - Journal of cardiovascular pharmacology

ER -

The effect of treatment with nitrendipine and other calcium channel blockers on the physiologic and pathologic changes caused by hypoxia in rats

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this