The effect of treatment with nitrendipine and other calcium channel blockers on the physiologic and pathologic changes caused by hypoxia in rats

John R. Michael; Thomas P. Kennedy; Philip Buescher; Imad Farrukh; Peter C. Rock; Gail Gurtner; Suzanne M. de la Monte; Grover M. Hutchins

doi:10.1097/00005344-198700094-00010

The effect of treatment with nitrendipine and other calcium channel blockers on the physiologic and pathologic changes caused by hypoxia in rats

John R. Michael, Thomas P. Kennedy, Philip Buescher, Imad Farrukh, Peter C. Rock, Gail Gurtner, Suzanne M. de la Monte, Grover M. Hutchins

Research output: Contribution to journal › Article › peer-review

Abstract

Nitrendipine and other calcium channel blokers acutely inhibit hypoxic pulmonary vasoconstriction and show promise in the prevention of the pulmonary vascular and cardiac changes produced by chronic alveolar hypoxia. This paper reviews the current information available from animal and clinical studies.

Original language	English (US)
Pages (from-to)	S61-S65
Journal	Journal of cardiovascular pharmacology
Volume	9
DOIs	https://doi.org/10.1097/00005344-198700094-00010
State	Published - 1987
Externally published	Yes

Keywords

Alveolar hypoxia
Nitrendipine
Pulmonary and cardiac changes

ASJC Scopus subject areas

Pharmacology
Cardiology and Cardiovascular Medicine

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10.1097/00005344-198700094-00010

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Michael, J. R., Kennedy, T. P., Buescher, P., Farrukh, I., Rock, P. C., Gurtner, G., de la Monte, S. M., & Hutchins, G. M. (1987). The effect of treatment with nitrendipine and other calcium channel blockers on the physiologic and pathologic changes caused by hypoxia in rats. Journal of cardiovascular pharmacology, 9, S61-S65. https://doi.org/10.1097/00005344-198700094-00010

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abstract = "Nitrendipine and other calcium channel blokers acutely inhibit hypoxic pulmonary vasoconstriction and show promise in the prevention of the pulmonary vascular and cardiac changes produced by chronic alveolar hypoxia. This paper reviews the current information available from animal and clinical studies.",

keywords = "Alveolar hypoxia, Nitrendipine, Pulmonary and cardiac changes",

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AU - Michael, John R.

AU - Kennedy, Thomas P.

AU - Buescher, Philip

AU - Farrukh, Imad

AU - Rock, Peter C.

AU - Gurtner, Gail

AU - de la Monte, Suzanne M.

AU - Hutchins, Grover M.

PY - 1987

Y1 - 1987

N2 - Nitrendipine and other calcium channel blokers acutely inhibit hypoxic pulmonary vasoconstriction and show promise in the prevention of the pulmonary vascular and cardiac changes produced by chronic alveolar hypoxia. This paper reviews the current information available from animal and clinical studies.

AB - Nitrendipine and other calcium channel blokers acutely inhibit hypoxic pulmonary vasoconstriction and show promise in the prevention of the pulmonary vascular and cardiac changes produced by chronic alveolar hypoxia. This paper reviews the current information available from animal and clinical studies.

KW - Alveolar hypoxia

KW - Nitrendipine

KW - Pulmonary and cardiac changes

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The effect of treatment with nitrendipine and other calcium channel blockers on the physiologic and pathologic changes caused by hypoxia in rats

Abstract

Keywords

ASJC Scopus subject areas

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