The determination of serotonin (5-hydroxytryptamine) in human blood

T. Phillip Waalkes

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


A sensitive fluorometric method for serotonin assay in human whole blood (and plasma) has been described. After precipitation of the blood proteins, serotonin is extracted from a basic solution into organic solvents and is purified and concentrated by means of an ion exchange medium, cotton acid succinate, or by extraction into acid. The values for blood from 21 patients are given and discussed.

Original languageEnglish (US)
Pages (from-to)824-829
Number of pages6
JournalThe Journal of laboratory and clinical medicine
Issue number5
StatePublished - May 1959

ASJC Scopus subject areas

  • Pathology and Forensic Medicine


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