The Dark Side of Estrogen Stops Translation to Induce Apoptosis

Heather M. Lamb; J. Marie Hardwick

doi:10.1016/j.molcel.2019.08.022

The Dark Side of Estrogen Stops Translation to Induce Apoptosis

Heather M. Lamb, J. Marie Hardwick

Bloomberg School of Public Health

Research output: Contribution to journal › Short survey › peer-review

3 Scopus citations

Abstract

The role of hormones in triggering cell death has been controversial. In this issue of Molecular Cell, Li et al. (2019) have defined a molecular pathway where an unexpected estrogen receptor, phosphodiesterase 3A, allows its partner Schlafen-12 to inhibit survival pathways, ultimately leading to apoptosis.

Original language	English (US)
Pages (from-to)	1087-1089
Number of pages	3
Journal	Molecular cell
Volume	75
Issue number	6
DOIs	https://doi.org/10.1016/j.molcel.2019.08.022
State	Published - Sep 19 2019

ASJC Scopus subject areas

Molecular Biology
Cell Biology

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10.1016/j.molcel.2019.08.022

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@article{18ab26b64f884babb696857d97819edf,

title = "The Dark Side of Estrogen Stops Translation to Induce Apoptosis",

abstract = "The role of hormones in triggering cell death has been controversial. In this issue of Molecular Cell, Li et al. (2019) have defined a molecular pathway where an unexpected estrogen receptor, phosphodiesterase 3A, allows its partner Schlafen-12 to inhibit survival pathways, ultimately leading to apoptosis.",

author = "Lamb, {Heather M.} and Hardwick, {J. Marie}",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",

year = "2019",

month = sep,

day = "19",

doi = "10.1016/j.molcel.2019.08.022",

language = "English (US)",

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T1 - The Dark Side of Estrogen Stops Translation to Induce Apoptosis

AU - Lamb, Heather M.

AU - Hardwick, J. Marie

PY - 2019/9/19

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N2 - The role of hormones in triggering cell death has been controversial. In this issue of Molecular Cell, Li et al. (2019) have defined a molecular pathway where an unexpected estrogen receptor, phosphodiesterase 3A, allows its partner Schlafen-12 to inhibit survival pathways, ultimately leading to apoptosis.

AB - The role of hormones in triggering cell death has been controversial. In this issue of Molecular Cell, Li et al. (2019) have defined a molecular pathway where an unexpected estrogen receptor, phosphodiesterase 3A, allows its partner Schlafen-12 to inhibit survival pathways, ultimately leading to apoptosis.

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U2 - 10.1016/j.molcel.2019.08.022

DO - 10.1016/j.molcel.2019.08.022

M3 - Short survey

C2 - 31539505

AN - SCOPUS:85071627002

SN - 1097-2765

VL - 75

SP - 1087

EP - 1089

JO - Molecular cell

JF - Molecular cell

IS - 6

ER -

The Dark Side of Estrogen Stops Translation to Induce Apoptosis

Abstract

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