The D2 receptor: Love it and leave it

D. Pickar

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Occupancy of the D2 receptor has been a foundation for the mechanism of antipsychotic action for over two decades. The introduction of atypical antipsychotics and their multiple receptor profiles coupled with functional brain imaging technology has raised questions about what once was considered to be a very tight concept. We address controversial facets to the D2 receptor's involvement in the antipsychotic mechanism and point to future clinical research directions.

Original languageEnglish (US)
Pages (from-to)101-102
Number of pages2
JournalMolecular Psychiatry
Issue number2
StatePublished - 1998
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Psychiatry and Mental health


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