Abstract
Age-related macular degeneration (AMD) is a complex disease with genetic, environmental, and demographic risk factors (see previous chapters). In recent years, there has been growing evidence that the inflammatory processes, including dysregulation of the complement system, play a major role in the pathogenesis of AMD. The discovery of genetic polymorphisms in genes coding for complement proteins that affect patients’ susceptibility to AMD propelled research in establishing the complement system as a key component in the pathogenesis of AMD [1].
Original language | English (US) |
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Title of host publication | Age-Related Macular Degeneration |
Publisher | Springer Berlin Heidelberg |
Pages | 65-76 |
Number of pages | 12 |
ISBN (Electronic) | 9783642221071 |
ISBN (Print) | 9783642221064 |
DOIs | |
State | Published - Jan 1 2013 |
ASJC Scopus subject areas
- Medicine(all)