TY - JOUR
T1 - The clinical spectrum and early diagnosis of Dawson's encephalitis. With preliminary notes on treatment
AU - Freeman, John M.
N1 - Funding Information:
From the Department of Pediatrics and Human Development, Stanford University School of Medicine. Supported in part by Public Health Research Grant No. F.R. 70 from the General Clinical Research Center Branch, Division of Facilities and Resources, by the Lt. Joseph P. Kennedy, Jr., Foundation, and by National Institutes of Health Grant No. HD-02147.
PY - 1969/10
Y1 - 1969/10
N2 - Dawson's encephalitis is a progressive, fatal, degenerative disease of the central nervous system due to the measles virus. The clinical course of progressive intellectual and personality changes, myoclonic seizures, and increasing neurologic deficit may progress rapidly over several weeks. Early diagnosis depends on clinical awareness and may be confirmed by electroencephalography, spinal fluid gamma globulin levels, and measles antibody titers. Early diagnosis is imperative if therapy is to result in a functional child. The preliminary results of treatment with pyran copolymer and 5-bromo-2-deoxyuridine are presented.
AB - Dawson's encephalitis is a progressive, fatal, degenerative disease of the central nervous system due to the measles virus. The clinical course of progressive intellectual and personality changes, myoclonic seizures, and increasing neurologic deficit may progress rapidly over several weeks. Early diagnosis depends on clinical awareness and may be confirmed by electroencephalography, spinal fluid gamma globulin levels, and measles antibody titers. Early diagnosis is imperative if therapy is to result in a functional child. The preliminary results of treatment with pyran copolymer and 5-bromo-2-deoxyuridine are presented.
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U2 - 10.1016/S0022-3476(69)80454-3
DO - 10.1016/S0022-3476(69)80454-3
M3 - Article
C2 - 4185707
AN - SCOPUS:0014594755
SN - 0022-3476
VL - 75
SP - 590
EP - 603
JO - The Journal of pediatrics
JF - The Journal of pediatrics
IS - 4
ER -