R5020 (17,21 -dimethyl -19 -nor -4,9 -pregnadiene-3,20-dione), a synthetic progestin, was tested for its binding to purified human transcortin, albumin and human serum. Scatchard analysis showed that R5020 bound relatively weakly to transcortin (Kass = 8 × 106M–1); in 20% human serum or albumin greater than 90% was bound with low Kass and an indeterminate number of binding sites.
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Clinical Biochemistry
- Biochemistry, medical